Human epidermal growth factor receptor (HER) 2 (HER2) is overexpressed in 20–30% of
breast cancers. HER2 is a preferred target for treating HER2-positive breast cancer …

Human epidermal growth factor receptor 2 (HER2)-positive breast cancer has a high
metastatic potential. Monoclonal antibodies (mAbs) that target HER2, such as trastuzumab …

An estimated 15–20% of breast cancers overexpress human epidermal growth factor
receptor 2 (HER2/ERBB2/neu). Two small-molecule tyrosine kinase inhibitors (TKIs) …

Feline mammary carcinoma (FMC) is a common aggressive malignancy with a low survival
rate that lacks viable therapeutic options beyond mastectomy. Recently, increasing efforts …

Malignant pleural mesothelioma (MPM) is a rare and aggressive malignant disease affecting
the mesothelium, commonly associated to asbestos exposure. Therapeutic actions are …

Purpose: TGFβ-induced epithelial-to-myofibroblast transition (EMyT) of lens cells has been
linked to the most common vision-disrupting complication of cataract surgery—namely …

Simple Summary Mammary tumors are common in cats, presenting an aggressive behavior
with high tumor recurrence. Therefore, new and efficient therapeutic protocols are urgent …

Malignant mesothelioma (MM) is a rare orphan aggressive neoplasia with low survival rates.
Among the other signaling pathways, ErbB receptors and Hh signaling are deregulated in …

Several attempts have been made to develop targeted therapies for malignant
mesothelioma (MM), an aggressive tumour with a poor prognosis. In this study we evaluated …

Feline mammary carcinoma (FMC) is a common neoplasia in cat, being HER2-positive the
most prevalent subtype. In woman's breast cancer, tyrosine kinase inhibitors (TKi) are used …