The Japanese clinical practice guidelines for management of sepsis and septic shock 2020 (J-SSCG 2020)

M Egi, H Ogura, T Yatabe, K Atagi, S Inoue, T Iba… - Journal of intensive …, 2021 - Springer
Abstract The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic
Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis …

Comparison of culture-negative and culture-positive sepsis or septic shock: a systematic review and meta-analysis

Y Li, J Guo, H Yang, H Li, Y Shen, D Zhang - Critical Care, 2021 - Springer
Background Mortality and other clinical outcomes between culture-negative and culture-
positive septic patients have been documented inconsistently and are very controversial. A …

Targeted metagenomic sequencing-based approach applied to 2146 tissue and body fluid samples in routine clinical practice

L Flurin, MJ Wolf, MM Mutchler… - Clinical Infectious …, 2022 - academic.oup.com
Background The yield of next-generation sequencing (NGS) added to a Sanger sequencing–
based 16S ribosomal RNA (rRNA) gene polymerase chain reaction (PCR) assay was …

Bacteremic sepsis leads to higher mortality when adjusting for confounders with propensity score matching

L Mellhammar, F Kahn, C Whitlow, T Kander… - Scientific reports, 2021 - nature.com
One can falsely assume that it is well known that bacteremia is associated with higher
mortality in sepsis. Only a handful of studies specifically focus on the comparison of culture …

A multi-mRNA host-response molecular blood test for the diagnosis and prognosis of acute infections and sepsis: proceedings from a clinical advisory panel

J Ducharme, WH Self, TM Osborn… - Journal of personalized …, 2020 - mdpi.com
Current diagnostics are insufficient for diagnosis and prognosis of acute infections and
sepsis. Clinical decisions including prescription and timing of antibiotics, ordering of …

A comparison of sepsis-2 (systemic inflammatory response syndrome based) to sepsis-3 (sequential organ failure assessment based) definitions—a multicenter …

M Engoren, T Seelhammer, RE Freundlich… - Critical care …, 2020 - journals.lww.com
Objectives: Recently, the definition of sepsis has changed from a physiologic derangement
(Sepsis-1 and-2) to organ dysfunction (Sepsis-3) based. We sought to determine the …

Culture-negative sepsis

J Thorndike, MH Kollef - Current opinion in critical care, 2020 - journals.lww.com
Owing to the difficulty inherent in studying the lack of positive data, and to the uncertainty
surrounding diagnosis in patients with culture-negative sepsis, prospective data to guide …

Epidemiology, Clinical Features, and Antimicrobial Resistance of Invasive Escherichia Coli Disease in Patients Admitted in Tertiary Care Hospitals

J Doua, J Geurtsen, J Rodriguez-Baño… - Open forum …, 2023 - academic.oup.com
Abstract Background Invasive Escherichia coli disease (IED), including bloodstream
infection, sepsis, and septic shock, can lead to high hospitalization and mortality rates. This …

Comparison of clinical characteristics and outcomes between positive and negative blood culture septic patients: a retrospective cohort study

L Yang, Y Lin, J Wang, J Song, B Wei… - Infection and Drug …, 2021 - Taylor & Francis
Background Few studies have studied the relationship between blood culture and mortality
in sepsis patients. The aim of this study was to compare the characteristics and outcomes of …

Fever and infections in surgical intensive care: an American Association for the surgery of trauma critical care committee clinical consensus document

E Nohra, RD Appelbaum, MS Farrell… - Trauma Surgery & …, 2024 - tsaco.bmj.com
The evaluation and workup of fever and the use of antibiotics to treat infections is part of
daily practice in the surgical intensive care unit (ICU). Fever can be infectious or non …