Prostate Cancer Biomarkers: From diagnosis to prognosis and precision-guided therapeutics

M Adamaki, V Zoumpourlis - Pharmacology & therapeutics, 2021 - Elsevier
Prostate cancer (PCa) is one of the most commonly diagnosed malignancies and among the
leading causes of cancer-related death worldwide. It is a highly heterogeneous disease …

[HTML][HTML] Functional outcomes of cerebellar malformations

JS Gill, RV Sillitoe - Frontiers in cellular neuroscience, 2019 - frontiersin.org
The cerebellum is well-established as a primary center for controlling sensorimotor
functions. However, recent experiments have demonstrated additional roles for the …

Joint dimension reduction and clustering analysis of single-cell RNA-seq and spatial transcriptomics data

W Liu, X Liao, Y Yang, H Lin, J Yeong… - Nucleic acids …, 2022 - academic.oup.com
Dimension reduction and (spatial) clustering is usually performed sequentially; however, the
low-dimensional embeddings estimated in the dimension-reduction step may not be …

Advances in cerebral palsy biomarkers

ZA Savasan, SK Kim, KJ Oh, SF Graham - Advances in clinical chemistry, 2021 - Elsevier
Cerebral palsy (CP), defined as a group of nonprogressive disorders of movement and
posture, is the most common cause of severe neurodisability in children. The prevalence of …

[HTML][HTML] PAFAH1B3 is a KLF9 target gene that promotes proliferation and metastasis in pancreatic cancer

C Dong, J Yao, Z Wu, J Hu, L Sun, Z Wu, J Yan… - Scientific Reports, 2024 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal human malignancies.
Uncontrolled cell proliferation, invasion and migration of pancreatic cancer cells are the …

Integrated transcriptome analyses revealed key target genes in mouse models of autism

W Duan, K Wang, Y Duan, X Chu, R Ma, P Hu… - Autism …, 2020 - Wiley Online Library
Genetic mutations are the major pathogenic factor of Autism Spectrum Disorder (ASD). In
recent years, more and more ASD risk genes have been revealed, among which there are a …

[HTML][HTML] Gene editing in monogenic autism spectrum disorder: animal models and gene therapies

N Wang, L Lv, X Huang, M Shi, Y Dai, Y Wei… - Frontiers in Molecular …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a lifelong neurodevelopmental disease, and its diagnosis
is dependent on behavioral manifestation, such as impaired reciprocal social interactions …

[HTML][HTML] Врожденные церебральные параличи: генетическая природа и нозологическая целостность

ПЛ Соколов, НВ Чебаненко, ВП Зыков… - Русский журнал …, 2020 - cyberleninka.ru
В обзоре представлен анализ 73 полнотекстовых статей, источником которых были
базы Medline, OMIM, NCBI, Pubmed, Scopus, eLibrary. ru. Рассмотрены и …

Engrailed‐2 is a cell autonomous regulator of neurogenesis in cultured hippocampal neural stem cells

M Durens, M Soliman, J Millonig… - Developmental …, 2021 - Wiley Online Library
Abnormalities in genes that regulate early brain development are known risk factors for
neurodevelopmental disorders. Engrailed‐2 (En2) is a homeodomain transcription factor …

Congenital cerebral palsy: genetic cause and nosological integrity

PI Sokolov, NV Chebanenko, VP Zykov… - Russian Journal of …, 2021 - rjdn.abvpress.ru
The review provides an analysis of 73 full-text articles, the source of which was the Medline,
OMIM, NCBI, Pubmed, Scopus, eLibrary. ru databases. The data of studies of the main …