Intranasal piperine-loaded chitosan nanoparticles as brain-targeted therapy in Alzheimer's disease: optimization, biological efficacy, and potential toxicity

YSR Elnaggar, SM Etman, DA Abdelmonsif… - Journal of …, 2015 - Elsevier
Piperine (PIP) is a phytopharmaceutical with reported neuroprotective potential in
Alzheimer's disease (AD). Oral PIP delivery suffers from its hydrophobicity and pre-systemic …

Interaction between alcohol and exercise: physiological and haematological implications

MS El-Sayed, N Ali, ZES Ali - Sports Medicine, 2005 - Springer
Alcohol use, particularly excessive alcohol consumption is one of the most serious health
risks in the world. A relationship between sport, exercise and alcohol consumption is clear …

The rutin/β-cyclodextrin interactions in fully aqueous solution: spectroscopic studies and biological assays

ML Calabro, S Tommasini, P Donato… - … of pharmaceutical and …, 2005 - Elsevier
In the present work the feasibility of β-cyclodextrin complexation was explored, as a tool for
improving the aqueous solubility and antioxidant efficacy of rutin. By means of 1H NMR, UV …

Mitigating effect of chrysin loaded solid lipid nanoparticles against Amyloid β25–35 induced oxidative stress in rat hippocampal region: An efficient formulation …

A Vedagiri, S Thangarajan - Neuropeptides, 2016 - Elsevier
Alzheimer's disease (AD) is the most prevalent form of dementia. Amyloid-β 25–35 (Aβ 25–
35), a well-established neurotoxicant, is reported to be involved in the etiology of AD …

[HTML][HTML] Protective effect of rutin on the antioxidant genes expression in hypercholestrolemic male Westar rat

SS Al-Rejaie, AM Aleisa, MM Sayed-Ahmed… - … and alternative medicine, 2013 - Springer
Background High-cholesterol diet (HCD) increases the oxidative stress in different tissues
leading to many diseases. Rutin (RT) is a natural flavonoid (vitamin p), which possesses an …

Effects of α-and β-cyclodextrin complexation on the physico-chemical properties and antioxidant activity of some 3-hydroxyflavones

ML Calabrò, S Tommasini, P Donato, D Raneri… - … of pharmaceutical and …, 2004 - Elsevier
Inclusion complexes of some flavonols (3-hydroxyflavone, morin and quercetin) have been
obtained with α-and β-cyclodextrins, by the co-evaporation method. Different analytical …

Oxidative damage during chagasic cardiomyopathy development: role of mitochondrial oxidant release and inefficient antioxidant defense

JJ Wen, G Vyatkina, N Garg - Free Radical Biology and Medicine, 2004 - Elsevier
In this study, we evaluated the oxidant status and antioxidant defense capabilities of the
heart during the course of Trypanosoma cruzi infection and disease development in a …

Agrimonia eupatoria protects against chronic ethanol-induced liver injury in rats

SJ Yoon, EJ Koh, CS Kim, OP Zee, JH Kwak… - Food and Chemical …, 2012 - Elsevier
This study examined the hepatoprotective effects of Agrimonia eupatoria water extract (AE)
against chronic ethanol-induced liver injury. Rats were fed a Lieber–DeCarli liquid diet for …

Effect of ethanol on liver antioxidant defense systems: Adose dependent study

SK Das, DM Vasudevan - Indian Journal of Clinical Biochemistry, 2005 - Springer
Alcohol induced oxidative stress is linked to the metabolism of ethanol. In this study it has
been observed that administration of ethanol in lower concentration caused gain in body …

The association between frequency of vigorous physical activity and hepatobiliary cancers in the NIH-AARP Diet and Health Study

G Behrens, CE Matthews, SC Moore… - European journal of …, 2013 - Springer
Despite a potential preventive effect of physical activity on hepatobiliary cancer, little
information is available on the relation between the two. We studied the association …