The blood–brain barrier (BBB) is an important physiological barrier that separates the
central nervous system (CNS) from the peripheral circulation, which contains inflammatory …

The blood vessels vascularizing the central nervous system exhibit a series of distinct
properties that tightly control the movement of ions, molecules, and cells between the blood …

Brain malignancies encompass a range of primary and metastatic cancers, including low-
grade and high-grade gliomas and brain metastases (BrMs) originating from diverse …

The blood-brain barrier (BBB) has been a great hurdle for brain drug delivery. The BBB in
healthy brain is a diffusion barrier essential for protecting normal brain function by impeding …

The adult quiescent blood–brain barrier (BBB), a structure organised by endothelial cells
through interactions with pericytes, astrocytes, neurons and microglia in the neurovascular …

Historically, multiple sclerosis (MS) has been viewed as being primarily driven by T cells.
However, the effective use of anti-CD20 treatment now also reveals an important role for B …

The blood–brain barrier (BBB) has shown to be a significant obstacle to brain medication
delivery. The BBB in a healthy brain is a diffusion barrier that prevents most substances from …

Physical or mental stress leads to neuroplasticity in the brain and increases the risk of
depression and anxiety. Stress exposure causes the dysfunction of peripheral T …

T cells are central to the pathogenesis of lupus nephritis (LN), a common complication of
systemic lupus erythematosus (SLE). CD6 and its ligand, activated leukocyte cell adhesion …

Over the most recent decades, the development of new biological platforms to study disease
progression and drug efficacy has been of great interest due to the high increase in the rate …