Antitumor mechanisms of molecules secreted by Trypanosoma cruzi in colon and breast cancer: A review
S Sadr, S Ghiassi, N Lotfalizadeh… - Anti-Cancer Agents …, 2023 - ingentaconnect.com
Background: Molecules secreted by Trypanosoma cruzi (T. cruzi) have beneficial effects on
the immune system and can fight against cancer by inhibiting the growth of tumor cells …
the immune system and can fight against cancer by inhibiting the growth of tumor cells …
[HTML][HTML] Fifteen Years after the Definition of Trypanosoma cruzi DTUs: What Have We Learned?
B Zingales, AM Macedo - Life, 2023 - mdpi.com
Trypanosoma cruzi, the protozoan causative of Chagas disease (ChD), exhibits striking
genetic and phenotypic intraspecific diversity, along with ecoepidemiological complexity …
genetic and phenotypic intraspecific diversity, along with ecoepidemiological complexity …
[HTML][HTML] SBC guideline on the diagnosis and treatment of patients with cardiomyopathy of chagas disease–2023
JA Marin-Neto, A Rassi Jr, GMM Oliveira… - Arquivos Brasileiros …, 2023 - SciELO Brasil
SciELO - Brazil - Diretriz da SBC sobre Diagnóstico e Tratamento de Pacientes com
Cardiomiopatia da Doença de Chagas – 2023 Diretriz da SBC sobre Diagnóstico e Tratamento …
Cardiomiopatia da Doença de Chagas – 2023 Diretriz da SBC sobre Diagnóstico e Tratamento …
Structure-Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors
MG Thomas, K McGonagle, P Rowland… - Journal of Medicinal …, 2023 - ACS Publications
There is an urgent need for new treatments for Chagas disease, a parasitic infection which
mostly impacts South and Central America. We previously reported on the discovery of …
mostly impacts South and Central America. We previously reported on the discovery of …
[HTML][HTML] Chagas disease: a silent threat for dogs and humans
J Durães-Oliveira, J Palma-Marques, C Moreno… - International Journal of …, 2024 - mdpi.com
Chagas disease (CD) is a vector-borne Neglected Zoonotic Disease (NZD) caused by a
flagellate protozoan, Trypanosoma cruzi, that affects various mammalian species across …
flagellate protozoan, Trypanosoma cruzi, that affects various mammalian species across …
[HTML][HTML] Diretriz da SBC sobre Diagnóstico e Tratamento de Pacientes com Cardiomiopatia da Doença de Chagas–2023
JA Marin-Neto, A Rassi Jr, GMM Oliveira… - Arquivos Brasileiros …, 2023 - SciELO Brasil
A DC (tripanossomíase americana) é entidade mórbida transmissível, potencialmente fatal,
causada pelo protozoário parasita T. cruzi e que integra o grupo de doenças tropicais …
causada pelo protozoário parasita T. cruzi e que integra o grupo de doenças tropicais …
Inside the Host: Understanding the Evolutionary Trajectories of Intracellular Parasitism
P Bartošová-Sojková, A Butenko… - Annual Review of …, 2024 - annualreviews.org
This review explores the origins of intracellular parasitism, an intriguing facet of symbiosis,
where one organism harms its host, potentially becoming deadly. We focus on three …
where one organism harms its host, potentially becoming deadly. We focus on three …
[HTML][HTML] Leishmaniasis and Chagas disease: Is there hope in nanotechnology to fight neglected tropical diseases?
DB Scariot, A Staneviciute, J Zhu, X Li… - Frontiers in Cellular …, 2022 - frontiersin.org
Nanotechnology is revolutionizing many sectors of science, from food preservation to
healthcare to energy applications. Since 1995, when the first nanomedicines started being …
healthcare to energy applications. Since 1995, when the first nanomedicines started being …
Silver and copper-benznidazole derivatives as potential antiparasitic metallodrugs: Synthesis, characterization, and biological evaluation
CC de Souza, JA de Azevedo-França, E Barrias… - Journal of Inorganic …, 2023 - Elsevier
Currently the only drug available to treat Chagas disease in Brazil is benznidazole (BZN).
Therefore, there is an urgent need to discover and develop new anti-Trypanosoma cruzi …
Therefore, there is an urgent need to discover and develop new anti-Trypanosoma cruzi …
Mode of action of p-quinone derivatives with trypanocidal activity studied by experimental and in silico models
A Ballesteros-Casallas, C Quiroga, C Ortiz… - European Journal of …, 2023 - Elsevier
Quinones are attractive pharmacological scaffolds for developing new agents for the
treatment of different transmissible and non-transmissible human diseases due to their …
treatment of different transmissible and non-transmissible human diseases due to their …