Alzheimer's disease (AD), a neurodegenerative brain disorder that affects millions of people
worldwide, is characterized by memory loss and cognitive decline. Low levels of …

Covering: 2000 to 2008 Over the last decade, it has become clear that antimicrobial drugs
are losing their effectiveness due to the evolution of pathogen resistance. There is therefore …

Phosphorus‐substituted heterocycles represent an important class of organophosphorus
compounds, which not only widely exist in biologically active pharmaceuticals …

Piperazine is one of the most sought heterocyclics for the development of new drug
candidates. This ring can be traced in a number of well established, commercially available …

The piperazine scaffold is a privileged structure frequently found in biologically active
compounds. Piperazine nucleus is found in many marketed drugs in the realm of …

The cobalt (II) complexes have been synthesized from the reaction of the cationic entities (3,
4-dimethylaniline (1) and histamine (2)) with metallic salt CoCl2⋅ 6H2O and thiocyanate ion …

This article purposes to provide insights to piperazine based molecular designs that will
facilitate drug discovery program in future. In our pursuit to summarize the reservoir of …

Carbon dioxide (CO 2) considerably contributes to the greenhouse effects and
consequently, to the global warming. Thus, reduction of CO 2 emissions/concentration in the …

Two new series of chalcones have been synthesized by reacting 1-(4-piperazin-1-yl-phenyl)
ethanone and 1-(2, 5-dichloro-3-thienyl)-1-ethanone with different substituted …

Benzotriazole (BtH) is an efficient ligand for the Cu-catalyzed N-arylation of imidazoles with
aryl and heteroaryl halides. A combination of CuI/BtH was found to be an efficient and …