Snakebite envenoming is a neglected tropical disease that kills> 100,000 people and
maims> 400,000 people every year. Impoverished populations living in the rural tropics are …

The field of mitochondrial ion channels has recently seen substantial progress, including the
molecular identification of some of the channels. An integrative approach using genetics …

Snakebite is classified by the WHO as a neglected tropical disease. Envenoming is a
significant public health problem in tropical and subtropical regions. Neurotoxicity is a key …

Phospholipases A2 (PLA2s) are abundant components of snake venoms, where they play
toxic and digestive roles. Despite having a similar three-dimensional structure, venom …

The phospholipase A2 (PLA2) and l-amino acid oxidase (LAAO) are two major enzymes
found in the venoms from most snake species. These enzymes have been structurally and …

There is increasing evidence suggesting that estrogens augment skeletal muscle
regeneration processes after injury. To study the contribution of estrogen receptors α and β …

The permeability transition pore (PTP) is an inner mitochondrial membrane channel that has
been thoroughly characterized functionally, yet remains an elusive molecular entity. The …

The active components of snake venoms encompass a complex and variable mixture of
proteins that produce a diverse, but largely stereotypical, range of pharmacologic effects and …

Infection with Helicobacter pylori is responsible for gastritis and gastroduodenal ulcers but is
also a high risk factor for the development of gastric adenocarcinoma and lymphoma. The …

An acute and highly reproducible motor axon terminal degeneration followed by complete
regeneration is induced by some animal presynaptic neurotoxins, representing an …