Cells migrate in multiple different ways depending on their environment, which includes the
extracellular matrix composition, interactions with other cells, and chemical stimuli. For all …

Neural crest cells are a transient embryonic cell population that migrate collectively to
various locations throughout the embryo to contribute a number of cell types to several …

In this article, we review physics-based models of collective cell motility. We discuss a range
of techniques at different scales, ranging from models that represent cells as simple self …

Contact inhibition of locomotion (CIL) is a process whereby a cell ceases motility or changes
its trajectory upon collision with another cell. CIL was initially characterized more than half a …

Macrophages are multifunctional cells that perform diverse roles in health and disease.
Emerging evidence has suggested that these innate immune cells might also be capable of …

Directed cell migration is a complex process that involves front–rear polarization,
characterized by cell adhesion and cytoskeleton-based protrusion, retraction, and …

The migratory dynamics of cells in physiological processes, ranging from wound healing to
cancer metastasis, rely on contact-mediated cell–cell interactions. These interactions play a …

Cell migration is a fundamental process that occurs during embryo development. Classic
studies using in vitro culture systems have been instrumental in dissecting the principles of …

The basement membrane (BM) is a thin layer of extracellular matrix (ECM) beneath nearly
all epithelial cell types that is critical for cellular and tissue function. It is composed of …

Cell migration is hypothesized to involve a cycle of behaviours beginning with leading edge
extension. However, recent evidence suggests that the leading edge may be dispensable …