Molecular mechanisms linking exercise to cancer prevention and treatment

P Hojman, J Gehl, JF Christensen, BK Pedersen - Cell metabolism, 2018 - cell.com
The benefits of exercise training for cancer patients are becoming increasingly evident.
Physical exercise has been shown to reduce cancer incidence and inhibit tumor growth …

Aging of mesenchymal stem cell: machinery, markers, and strategies of fighting

M Al-Azab, M Safi, E Idiiatullina, F Al-Shaebi… - Cellular & Molecular …, 2022 - Springer
Human mesenchymal stem cells (MSCs) are primary multipotent cells capable of
differentiating into osteocytes, chondrocytes, and adipocytes when stimulated under …

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight

FE Garrett-Bakelman, M Darshi, SJ Green, RC Gur… - Science, 2019 - science.org
INTRODUCTION To date, 559 humans have been flown into space, but long-duration (> 300
days) missions are rare (n= 8 total). Long-duration missions that will take humans to Mars …

Modern-day environmental factors in the pathogenesis of osteoarthritis

F Berenbaum, IJ Wallace, DE Lieberman… - Nature Reviews …, 2018 - nature.com
The prevalence of osteoarthritis (OA) is rising for reasons that are not fully understood. In this
Opinion article, we review the possibility that OA is an evolutionary mismatch disease, which …

Oxidative stress, aging, antioxidant supplementation and their impact on human health: An overview

G Martemucci, P Portincasa, A Di Ciaula… - Mechanisms of Ageing …, 2022 - Elsevier
Aging is characterized by a progressive loss of tissue and organ function due to genetic and
environmental factors, nutrition, and lifestyle. Oxidative stress is one the most important …

Aging hallmarks: the benefits of physical exercise

A Rebelo-Marques, A De Sousa Lages… - Frontiers in …, 2018 - frontiersin.org
World population has been continuously increasing and progressively aging. Aging is
characterized by a complex and intraindividual process associated with nine major cellular …

Mediterranean diet and the hallmarks of ageing

OM Shannon, AW Ashor, F Scialo, G Saretzki… - European Journal of …, 2021 - nature.com
Ageing is a multifactorial process associated with reduced function and increased risk of
morbidity and mortality. Recently, nine cellular and molecular hallmarks of ageing have …

[图书][B] Physical activity epidemiology

RK Dishman, GW Heath, MD Schmidt, IM Lee - 2021 - books.google.com
Physical Activity Epidemiology, Third Edition, provides a discussion of current studies
showing the influence of physical activity on disease. Updated with extensive new content in …

The fetal programming of telomere biology hypothesis: an update

S Entringer, K de Punder, C Buss… - … Transactions of the …, 2018 - royalsocietypublishing.org
Research on mechanisms underlying fetal programming of health and disease risk has
focused primarily on processes that are specific to cell types, organs or phenotypes of …

Telomeres and age-related diseases

HJ Gruber, MD Semeraro, W Renner, M Herrmann - Biomedicines, 2021 - mdpi.com
Telomeres are at the non-coding ends of linear chromosomes. Through a complex 3-
dimensional structure, they protect the coding DNA and ensure appropriate separation of …