Due to the increasing number of heart valve diseases, there is an urgent clinical need for off-
the-shelf tissue engineered heart valves. While significant progress has been made toward …

▪ Abstract For native and engineered biological tissues, there exist many physiological,
surgical, and medical device applications where multiaxial material characterization and …

We present formulations for compressible and incompressible hyperelastic thin shells which
can use general 3D constitutive models. The necessary plane stress condition is enforced …

This paper builds on a recently developed immersogeometric fluid–structure interaction
(FSI) methodology for bioprosthetic heart valve (BHV) modeling and simulation. It enhances …

Constitutive modeling is a cornerstone for stress analysis of mechanical behaviors of
biological soft tissues. Recently, it has been shown that machine learning (ML) techniques …

The biomechanical response of normal and pathologic human abdominal aortic tissue to
uniaxial loading conditions is insufficient for the characterization of its three-dimensional …

A three-dimensional fluid–structure interaction (FSI) framework for rigid bodies has been
extended to deformable soft tissue by coupling a sharp-interface immersed boundary …

The microstructure of tissues and tissue equivalents (TEs) plays a critical role in determining
the mechanical properties thereof. One of the key challenges in constitutive modeling of TEs …

The collagen fiber alignment and biomechanical behavior of naturally occurring extracellular
matrix (ECM) scaffolds are important considerations for the design of medical devices from …

The mechanical testing of anisotropic nonlinearly elastic solids is a topic of considerable
and increasing interest. The results of such testing are important, in particular, for the …