Emergence of resistance by bacterial and fungal stains towards existing antimicrobial
agents is one of the major problem as well as motivation to synthesize a new class of …

Plants produce and release a vast variety of secondary metabolites with diversified
functions, and possess ecological, toxicological and biological effects that mimic the …

Antimicrobial resistance presents us with a potential global crisis as it undermines the
abilities of conventional antibiotics to combat pathogenic microbes. The history of …

In an effort to develop new antibacterial drugs, some novel bisindolylmethane derivatives
containing Schiff base moieties were prepared and screened for their antibacterial activity …

Coumarins are well recognized naturally occurring compounds which isolated and present
in large number of compounds in the plant kingdom. Mostly occur in higher plants, richest …

Bisindolylmethane and its derivatives are pharmacologically active and applicable in the
field of pharmaceutical chemistry. Bisindolylmethanes have a variety of biological activities …

Dipolar cycloaddition between a chiral nitrone and N-substituted maleimides afforded
unprecedented enantiopure spiro-fused heterocycles in good yields with a high enantio-and …

Featured Application Coumarin derivatives are promising candidates for developing novel
plant-protection products of the new generation, which meet all requirements of modern …

In the present investigation, a series of coumarin-based compounds containing a chalcone
moiety were studied for their in vitro and in silico properties. The DFT global chemical …

Background: As coumarin derivatives are known to prevent and treat various diseases, they
have attracted the attention of medicinal chemists. They have strong potential as drugs …