Automated synapse-level reconstruction of neural circuits in the larval zebrafish brain

F Svara, D Förster, F Kubo, M Januszewski… - Nature …, 2022 - nature.com
Dense reconstruction of synaptic connectivity requires high-resolution electron microscopy
images of entire brains and tools to efficiently trace neuronal wires across the volume. To …

Anatomy and function of retinorecipient arborization fields in zebrafish

H Baier, MF Wullimann - Journal of Comparative Neurology, 2021 - Wiley Online Library
Abstract In 1994, Burrill and Easter described the retinal projections in embryonic and larval
zebrafish, introducing the term “arborization fields”(AFs) for the retinorecipient areas. AFs …

A brainstem integrator for self-location memory and positional homeostasis in zebrafish

E Yang, MF Zwart, B James, M Rubinov, Z Wei… - Cell, 2022 - cell.com
To track and control self-location, animals integrate their movements through space.
Representations of self-location are observed in the mammalian hippocampal formation, but …

The Visual Systems of Zebrafish

H Baier, EK Scott - Annual Review of Neuroscience, 2024 - annualreviews.org
The zebrafish visual system has become a paradigmatic preparation for behavioral and
systems neuroscience. Around 40 types of retinal ganglion cells (RGCs) serve as matched …

Retina-derived signals control pace of neurogenesis in visual brain areas but not circuit assembly

S Sherman, I Arnold-Ammer, MW Schneider… - Nature …, 2023 - nature.com
Brain development is orchestrated by both innate and experience-dependent mechanisms,
but their relative contributions are difficult to disentangle. Here we asked if and how central …

Molecular classification of zebrafish retinal ganglion cells links genes to cell types to behavior

Y Kölsch, J Hahn, A Sappington, M Stemmer… - Neuron, 2021 - cell.com
Retinal ganglion cells (RGCs) form an array of feature detectors, which convey visual
information to central brain regions. Characterizing RGC diversity is required to understand …

A single-cell resolution gene expression atlas of the larval zebrafish brain

I Shainer, E Kuehn, E Laurell, M Al Kassar… - Science …, 2023 - science.org
The advent of multimodal brain atlases promises to accelerate progress in neuroscience by
allowing in silico queries of neuron morphology, connectivity, and gene expression. We …

Recording physiological history of cells with chemical labeling

MC Huppertz, J Wilhelm, V Grenier, MW Schneider… - Science, 2024 - science.org
Recordings of the physiological history of cells provide insights into biological processes, yet
obtaining such recordings is a challenge. To address this, we introduce a method to record …

Whole brain functional recordings at cellular resolution in zebrafish larvae with 3D scanning multiphoton microscopy

M Bruzzone, E Chiarello, M Albanesi… - Scientific reports, 2021 - nature.com
Optical recordings of neuronal activity at cellular resolution represent an invaluable tool to
investigate brain mechanisms. Zebrafish larvae is one of the few model organisms where …

Development of the vertebrate retinal direction-selective circuit

NR Hamilton, AJ Scasny, AL Kolodkin - Developmental biology, 2021 - Elsevier
The vertebrate retina contains an array of neural circuits that detect distinct features in visual
space. Direction-selective (DS) circuits are an evolutionarily conserved retinal circuit motif …