Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …

Huntington's disease (HD) is a neurodegenerative disorder caused by a CAG expansion in
the HD gene. The disease is characterized by neurodegeneration, particularly in the striatum …

Since the identification of the causative gene in Huntington's disease (HD), a number of
animal models of this disorder have been developed. A frequently asked question is: which …

Huntington disease (HD) is caused by a CAG repeat expansion in the huntingtin (HTT)
gene. Although the length of this repeat is inversely correlated with age of onset (AOO), it …

Huntington's disease (HD) is an autosomal neurodegenerative disorder, characterized by
severe behavioral, cognitive, and motor deficits. Since the discovery of the huntingtin gene …

Huntington's disease (HD) is a hereditary neurodegenerative disorder that typically
manifests in midlife with motor, cognitive, and/or psychiatric symptoms. The disease is …

Huntington's disease (HD) is a fatal autosomal dominant neurodegenerative disease
caused by an increase in the number of polyglutamine residues in the huntingtin (Htt) …

The endocannabinoid system (ECS) exerts a modulatory effect of important functions such
as neurotransmission, glial activation, oxidative stress, or protein homeostasis …

Dopamine (DA) plays an essential role in the control of coordinated movements. Alterations
in DA balance in the striatum lead to pathological conditions such as Parkinson's and …

White matter abnormalities are a nearly universal pathological feature of neurodegenerative
disorders including Huntington disease (HD). A long-held assumption is that this white …