Outbreaks of multidrug-resistant bacteria present a frequent threat to vulnerable patient
populations in hospitals around the world. Intensive care unit (ICU) patients are particularly …

High-throughput RNA sequencing (RNA-seq) promises a comprehensive picture of the
transcriptome, allowing for the complete annotation and quantification of all genes and their …

Aedes aegypti and A. albopictus mosquitoes are the main vectors for dengue virus (DENV)
and other arboviruses, including Zika virus (ZIKV). Understanding the factors that affect …

GetOrganelle is a state-of-the-art toolkit to accurately assemble organelle genomes from
whole genome sequencing data. It recruits organelle-associated reads using a modified …

The subterranean world hosts up to one-fifth of all biomass, including microbial communities
that drive transformations central to Earth's biogeochemical cycles. However, little is known …

Lung infections with Mycobacterium abscessus, a species of multidrug-resistant
nontuberculous mycobacteria, are emerging as an important global threat to individuals with …

Whole-genome sequences are now available for many microbial species and clades,
however existing whole-genome alignment methods are limited in their ability to perform …

Background: Chloroplast genes and genomes are the most important genomic data for plant
phylogeny and DNA barcoding. Since the rapid development of high throughput sequencing …

Advances in deciphering the functional architecture of eukaryotic genomes have been
facilitated by recent breakthroughs in sequencing technologies, enabling a more …

No single genealogical reconstruction or typing method currently encompasses all levels of
bacterial diversity, from domain to strain. We propose ribosomal multilocus sequence typing …