U-47700 and its analogs: non-fentanyl synthetic opioids impacting the recreational drug market

MH Baumann, G Tocco, DM Papsun, AL Mohr… - Brain sciences, 2020 - mdpi.com
The recreational use of opioid drugs is a global threat to public health and safety. In
particular, an epidemic of opioid overdose fatalities is being driven by illicitly manufactured …

Novel synthetic opioids–toxicological aspects and analysis

I Tabarra, S Soares, T Rosado… - Forensic Sciences …, 2019 - academic.oup.com
Over the past few years, there has been an emerging number of new psychoactive drugs.
These drugs are frequently mentioned as “legal highs”,“herbal highs”,“bath salts” and …

Rapid lateral flow assays based on the quantification of magnetic nanoparticle labels for multiplexed immunodetection of small molecules: application to the …

NV Guteneva, SL Znoyko, AV Orlov, MP Nikitin… - Microchimica Acta, 2019 - Springer
A rapid lateral flow immunoassay is presented that uses carboxyl-modified
superparamagnetic nanoparticles as labels that can be quantified by highly sensitive multi …

Ultra-high-performance liquid chromatography-tandem mass spectrometry assay for quantifying fentanyl and 22 analogs and metabolites in whole blood, urine, and …

FP Busardò, J Carlier, R Giorgetti, A Tagliabracci… - Frontiers in …, 2019 - frontiersin.org
Recently, synthetic opioid-related overdose fatalities, led by illicitly manufactured fentanyl
and analogs, increased at an alarming rate, posing a global public health threat. New …

In silico prediction, LC-HRMS/MS analysis, and targeted/untargeted data-mining workflow for the profiling of phenylfentanyl in vitro metabolites

A Di Trana, P Brunetti, R Giorgetti, E Marinelli, S Zaami… - Talanta, 2021 - Elsevier
Illicit fentanyl and analogues have been involved in many fatalities and cases of intoxication
across the United States over the last decade, and are becoming a health concern in …

Targeted and untargeted detection of fentanyl analogues and their metabolites in hair by means of UHPLC-QTOF-HRMS

A Salomone, D Di Corcia, P Negri, M Kolia… - Analytical and …, 2021 - Springer
Detection of new psychoactive substances and synthetic opioids is generally performed by
means of targeted methods in mass spectrometry, as they generally provide adequate …

[PDF][PDF] Hair testing for doping agents. What is known and what remains to do

P Kintz, L Gheddar, A Ameline, N Arbouche… - Drug testing and …, 2020 - academia.edu
Testing for drugs in hair to document exposure is receiving more and more attention by
scientists and lawyers due to is long detection window, particularly when compared to blood …

Review of analytical methods for screening and quantification of fentanyl analogs and novel synthetic opioids in biological specimens

KB Palmquist, MT Truver, EN Shoff… - Journal of forensic …, 2023 - Wiley Online Library
Fentanyl, fentanyl analogs, and other novel synthetic opioids (NSO), including nitazene
analogs, prevail in forensic toxicology casework. Analytical methods for identifying these …

Determination of nine fentanyl drugs in hair samples by GC-MS/MS and LC-MS/MS

Q Wei, FH Su - ACS omega, 2022 - ACS Publications
We established GC-MS/MS and LC-MS/MS analysis methods for nine fentanyl drugs in hair
samples. Human hairs were prepared by soaking in a solution of water-dimethyl sulfoxide …

Development of an UPLC–MS/MS method for the analysis of 16 synthetic opioids in segmented hair, and evaluation of the polydrug history in fentanyl analogue users

MMR Fernández, SMR Wille, D Jankowski, V Hill… - Forensic science …, 2020 - Elsevier
Seizures of synthetic opioids have increased since 2012, with a 45% increase in synthetic
opioid related deaths between 2016 and 2017 in US. Recently, concerns have arisen …