Nuclear receptors (NRs) are transcription factors actively involved in many aspects of human
physiology and pathology, serving as sensors of stimuli, master regulators of downstream …

The significant biochemical and physiological effects of psychological stress are beginning
to be recognized as exacerbating common diseases, including osteoporosis. This review …

Introduction Sex differences in incidence, onset and course of schizophrenia suggest sex
hormones play a protective role in the pathophysiology. Such a role is also proposed for …

Chronic pain determines a substantial burden on individuals, employers, healthcare
systems, and society. Most of the affected patients report dissatisfaction with currently …

Purpose This review aims at investigating pathophysiological mechanisms in
spondyloarthritis (SpA). Analysis of genetic factors, immunological pathways, and …

Background: Breast cancer is considered to be 2nd most common cancer subtype
investigated worldwide. It is mainly prevalent in postmenopausal women. Estrogen Receptor …

The potential therapeutic utility of estrogens in schizophrenia is increasingly being
recognized. Raloxifene, a selective estrogen receptor modulator, appears to act similarly to …

Aim Endothelial dysfunction is considered a premature indication of atherosclerosis and
vessel damage and is present in the postmenopausal period. This study compares the …

In patients with postmenopausal osteoporosis low bone volume is associated with high
bone marrow adipose tissue (MAT). Moreover, high MAT is associated with increased …

Recent studies have shown that the selective estrogen receptor modulator (SERM)
raloxifene had pronounced protective effects against progressing brain damage after …