Ghrelin, an acylated peptide hormone of 28 amino acids, is an endogenous ligand of the
released growth hormone secretagogue receptor (GHSR). Ghrelin has been isolated from …

Obesity and insulin resistance have reached epidemic proportions. Obesogenic conditions
are associated with increased risk for the development of other comorbidities and obesity …

Objective Obesity-associated chronic inflammation, aka meta-inflammation, is a key
pathogenic driver for obesity-associated comorbidity. Growth hormone secretagogue …

Ghrelin is a small peptide with 28 amino acids, and has been characterized as the ligand of
the growth hormone secretagogue receptor (GHSR). In addition to its original function in …

Inflammation is an active defense response of the body against external stimuli. Long term
low-grade inflammation has been considered as a deteriorated factor for aging, cancer …

Ghrelin is a brain‐gut peptide, and the first 28‐peptide that was found in the gastric mucosa.
It has a growth hormone (GH)‐releasing hormone‐like effect and can potently promote the …

Abstract Interleukin-1β (IL-1β), a key pro-inflammatory cytokine, is majorly produced by
macrophages through NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) …

Whether the stomach influences the progression of nonalcoholic steatohepatitis (NASH)
remains largely unknown. Ghrelin, a 28‐amino acid gastric hormone, is critical for the …

Ghrelin, an orexigenic hormone released primarily from the gut, signals the hypothalamus to
stimulate growth hormone release, enhance appetite and promote weight gain. The ghrelin …

The stomach-derived hormone ghrelin regulates essential physiological functions. The
ghrelin receptor (GHSR) has ligand-independent actions; therefore, GHSR gene deletion …