[HTML][HTML] SARS-CoV-2 variant biology: immune escape, transmission and fitness

AM Carabelli, TP Peacock, LG Thorne… - Nature Reviews …, 2023 - nature.com
In late 2020, after circulating for almost a year in the human population, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …

[HTML][HTML] The evolution of SARS-CoV-2

PV Markov, M Ghafari, M Beer, K Lythgoe… - Nature Reviews …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …

SARS-CoV-2 evolution in the Omicron era

C Roemer, DJ Sheward, R Hisner, F Gueli… - Nature …, 2023 - nature.com
Abstract Since SARS-CoV-2 BA. 5 (Omicron) emerged and spread in 2022, Omicron
lineages have markedly diversified. Here we review the evolutionary trajectories and …

The evolution and biology of SARS-CoV-2 variants

A Telenti, EB Hodcroft… - Cold Spring …, 2022 - perspectivesinmedicine.cshlp.org
Our understanding of the still unfolding severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) pandemic would have been extremely limited without the study of the …

[HTML][HTML] Transmission of SARS-CoV-2 in free-ranging white-tailed deer in the United States

A Feng, S Bevins, J Chandler, TJ DeLiberto… - Nature …, 2023 - nature.com
SARS-CoV-2 is a zoonotic virus with documented bi-directional transmission between
people and animals. Transmission of SARS-CoV-2 from humans to free-ranging white-tailed …

Selection analysis identifies clusters of unusual mutational changes in Omicron lineage BA. 1 that likely impact Spike function

DP Martin, S Lytras, AG Lucaci, W Maier… - Molecular biology …, 2022 - academic.oup.com
Among the 30 nonsynonymous nucleotide substitutions in the Omicron S-gene are 13 that
have only rarely been seen in other SARS-CoV-2 sequences. These mutations cluster within …

[HTML][HTML] Host range, transmissibility and antigenicity of a pangolin coronavirus

YJ Hou, S Chiba, SR Leist, RM Meganck… - Nature …, 2023 - nature.com
The pathogenic and cross-species transmission potential of SARS-CoV-2-related
coronaviruses (CoVs) remain poorly characterized. Here we recovered a wild-type pangolin …

White-tailed deer (Odocoileus virginianus) may serve as a wildlife reservoir for nearly extinct SARS-CoV-2 variants of concern

LC Caserta, M Martins, SL Butt… - Proceedings of the …, 2023 - National Acad Sciences
The spillover of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from
humans to white-tailed deer (WTD) and its ability to transmit from deer to deer raised …

[HTML][HTML] After 2 years of the COVID-19 pandemic, translating One Health into action is urgent

T Lefrançois, D Malvy, L Atlani-Duault, D Benamouzig… - The Lancet, 2023 - thelancet.com
The world is coping with the health, societal, and economic consequences of more than 2
years of the COVID-19 pandemic. Emerging diseases caused by new pathogens, or re …

Evolution of the SARS-CoV-2 mutational spectrum

JD Bloom, AC Beichman, RA Neher… - Molecular Biology and …, 2023 - academic.oup.com
SARS-CoV-2 evolves rapidly in part because of its high mutation rate. Here, we examine
whether this mutational process itself has changed during viral evolution. To do this, we …