Antioxidant curcumin induces oxidative stress to kill tumor cells

Y Hu, L Cheng, S Du, K Wang… - Oncology Letters, 2023 - spandidos-publications.com
Curcumin is a plant polyphenol in turmeric root and a potent antioxidant. It binds to
antioxidant response elements for gene regulation by nuclear factor erythroid 2-related …

Navigating heme pathways: the breach of heme oxygenase and hemin in breast cancer

V Consoli, V Sorrenti, M Gulisano… - Molecular and Cellular …, 2024 - Springer
Breast cancer remains a significant global health challenge, with diverse subtypes and
complex molecular mechanisms underlying its development and progression. This review …

Hyperforin Enhances Heme Oxygenase-1 Expression Triggering Lipid Peroxidation in BRAF-Mutated Melanoma Cells and Hampers the Expression of Pro-Metastatic …

A Cardile, C Passarini, V Zanrè, A Fiore, M Menegazzi - Antioxidants, 2023 - mdpi.com
Hyperforin (HPF) is an acylphloroglucinol compound found abundantly in Hypericum
perforatum extract which exhibits antidepressant, anti-inflammatory, antimicrobial, and …

Proteomic analysis of the effect of hemin in breast cancer

GP Colo, K Schweitzer, GM Oresti, EG Alonso… - Scientific Reports, 2023 - nature.com
Heme, an iron-containing prosthetic group found in many proteins, carries out diverse
biological functions such as electron transfer, oxygen storage and enzymatic reactions …

Potential anticancer effect of free and nanoformulated Deferasirox for breast cancer treatment: in-vitro and in-vivo evaluation

ND Abdel-Wahab, MF Kabil… - Drug Development …, 2024 - Taylor & Francis
Background Breast cancer (BC) stands as the second-leading cause of mortality among
women worldwide. Many chemotherapeutic treatments for BC come with significant adverse …