Preclinical models of medication-related osteonecrosis of the jaw (MRONJ)
JI Aguirre, EJ Castillo, DB Kimmel - Bone, 2021 - Elsevier
Medication-related osteonecrosis of the jaw (MRONJ) is a potentially severe adverse event
affecting patients with cancer and patients with osteoporosis who have been treated with …
affecting patients with cancer and patients with osteoporosis who have been treated with …
Treatment perspectives for medication-related osteonecrosis of the jaw (MRONJ)
O Ristow, S Otto, M Troeltzsch… - Journal of Cranio …, 2015 - Elsevier
The medication-related osteonecrosis of the jaw (MRONJ) is believed to be a therapy-
resistant entity. Although the application of the recommended conservative and surgical …
resistant entity. Although the application of the recommended conservative and surgical …
Tooth extraction in patients receiving oral or intravenous bisphosphonate administration: a trigger for BRONJ development?
S Otto, M Tröltzsch, V Jambrovic, S Panya… - Journal of Cranio …, 2015 - Elsevier
Introduction Scientific debate outlines tooth extraction as a potential trigger for the onset of
bisphosphonate-related osteonecrosis of the jaw (BRONJ). Therefore, the aim of this study …
bisphosphonate-related osteonecrosis of the jaw (BRONJ). Therefore, the aim of this study …
A multicenter retrospective study of the risk factors associated with medication-related osteonecrosis of the jaw after tooth extraction in patients receiving oral …
T Hasegawa, A Kawakita, N Ueda, R Funahara… - Osteoporosis …, 2017 - Springer
Root amputation, extraction of a single tooth, bone loss or severe tooth mobility, and an
unclosed wound were significantly associated with increased risk of developing medication …
unclosed wound were significantly associated with increased risk of developing medication …
Osteonecrosis of the jaws (ONJ) in mice after extraction of teeth with periradicular disease
A Soundia, D Hadaya, N Esfandi, RS de Molon… - Bone, 2016 - Elsevier
Osteonecrosis of the jaws (ONJ) is a complication of antiresorptive medications, such as
denosumab or bisphosphonates, prescribed to patients with bone malignancy or …
denosumab or bisphosphonates, prescribed to patients with bone malignancy or …
Medication-related osteonecrosis of the jaw: a critical narrative review
AI Lorenzo-Pouso, J Bagán, L Bagán… - Journal of Clinical …, 2021 - mdpi.com
Background: Nearly two decades have passed since a paradoxical reaction in the orofacial
region to some bone modifying agents and other drugs was recognized, namely medication …
region to some bone modifying agents and other drugs was recognized, namely medication …
Rodents as an animal model for studying tooth extraction-related medication-related osteonecrosis of the jaw: assessment of outcomes
Objective To assess the outcomes of several rodent animal models for studying tooth
extraction-related medication-related osteonecrosis of the jaw (MRONJ). Design After a …
extraction-related medication-related osteonecrosis of the jaw (MRONJ). Design After a …
Pathogenesis of medication-related osteonecrosis of the jaw: a comparative study of in vivo and in vitro trials
H Holtmann, J Lommen, NR Kübler… - Journal of …, 2018 - journals.sagepub.com
Objective This study was performed to determine whether the results of prevailing in vivo
and in vitro studies offer a reliable model for investigation of medication-related …
and in vitro studies offer a reliable model for investigation of medication-related …
Etiopathogenesis of medication-related osteonecrosis of the jaws: a review
G Bassan Marinho Maciel, R Marinho Maciel… - Journal of Molecular …, 2024 - Springer
This study compiles the main hypotheses involved in the etiopathogenesis of medication-
related osteonecrosis of the jaw (MRONJ). A narrative review of the literature was …
related osteonecrosis of the jaw (MRONJ). A narrative review of the literature was …
In vivo effects of geranylgeraniol on the development of bisphosphonate-related osteonecrosis of the jaws
F Koneski, D Popovic-Monevska, I Gjorgoski… - Journal of Cranio …, 2018 - Elsevier
Background Bisphosphonate-related osteonecrosis of the jaws (BRONJ) is a complication of
the bisphosphonate (BP) treatment and its pathopysiology is still not fully understood. The …
the bisphosphonate (BP) treatment and its pathopysiology is still not fully understood. The …