Higenamine attenuates neuropathic pain by inhibition of NOX2/ROS/TRP/P38 mitogen-activated protein kinase/NF-ĸB signaling pathway

B Yang, S Ma, C Zhang, J Sun, D Zhang… - Frontiers in …, 2021 - frontiersin.org
Oxidative stress damage is known as one of the important factors that induce neuropathic
pain (NP). Using antioxidant therapy usually achieves an obvious curative effect and …

Antioxidant efficacy of esculetin against tert-butyl hydroperoxide-induced oxidative stress in HEK293 cells

WK Jung, SB Park, HY Yu, YH Kim, J Kim - Current Issues in Molecular …, 2022 - mdpi.com
Esculetin is an antioxidant and anti-inflammatory compound derived from coumarin.
Oxidative stress can cause overproduction of reactive oxygen species (ROS), which can …

Effect of Esculetin on Tert-Butyl Hydroperoxide-Induced Oxidative Injury in Retinal Pigment Epithelial Cells In Vitro

WK Jung, SB Park, HY Yu, YH Kim, J Kim - Molecules, 2022 - mdpi.com
Esculetin is a coumarin-derived compound with antioxidant and anti-inflammatory
properties. The current study aims to evaluate the therapeutic implications of esculetin on …

Investigation of cardiolipin oxidation products as a new endpoint for oxidative stress in C. elegans by means of online two-dimensional liquid chromatography and …

PO Helmer, MM Nicolai, V Schwantes… - Free Radical Biology …, 2021 - Elsevier
The investigation of neurodegenerative and age-related diseases is a highly relevant topic
in current research. Especially oxidative stress is thought to be the common underlying …

Arbutin Protects Retinal Pigment Epithelium Against Oxidative Stress by Modulating SIRT1/FOXO3a/PGC-1α/β Pathway

H Tang, H Du, X Kuang, H Huang, J Zeng… - Frontiers in …, 2022 - frontiersin.org
Age-related macular degeneration (AMD), which is the leading cause of blindness among
the elderly in western societies, is majorly accompanied by retinal pigment epithelium (RPE) …

Maternal zinc alleviates tert-butyl hydroperoxide-induced mitochondrial oxidative stress on embryonic development involving the activation of Nrf2/PGC-1α pathway

L Huang, W Gao, X He, T Yuan, H Zhang… - Journal of Animal …, 2023 - Springer
Background Mitochondrial dysfunction induced by excessive mitochondrial reactive oxygen
species (ROS) damages embryonic development and leads to growth arrest. Objective The …

Modulation of amyloid fibrillation of bovine β-lactoglobulin by selective methionine oxidation

S Maity, N Sepay, S Pal, S Sardar, H Parvej, S Pal… - RSC …, 2021 - pubs.rsc.org
Deposition of oxidation-modified proteins during normal aging and oxidative stress are
directly associated with systemic amyloidoses. Methionine (Met) is believed to be one of the …

Insulin ameliorates hypoxia-induced autophagy, endoplasmic reticular stress and apoptosis of myocardial cells: In vitro and ex vivo models

TJ Liu, YC Yeh, WL Lee, LC Wang, HW Lee… - European Journal of …, 2020 - Elsevier
Whether and how insulin counteracts the cytotoxic effects of hypoxia and improves
cardiomyocyte viability remains unclear. To achieve this aim, cultured neonatal rat …

[HTML][HTML] Shorter Leukocyte Telomere Length coupled with lower expression of Telomerase Genes in patients with Essential Hypertension

G Cheng, L Wang, M Dai, F Wei… - International Journal of …, 2020 - ncbi.nlm.nih.gov
Background: The essential hypertension (EH) pathophysiology remains poorly understood.
Many studies indicate that reduced leukocyte telomere length (LTL) is involved in the EH …

The Link Between 15-F2t-Isoprostane Activity and Acute Bovine Endothelial Inflammation Remains Elusive

AK Putman, LM Sordillo, GA Contreras - Frontiers in Veterinary …, 2022 - frontiersin.org
Modern dairy cattle suffer from increased incidence and severity of mastitis during major
physiological transitions of the lactation cycle. Oxidative stress, a condition resulting from …