Biolink Model: A universal schema for knowledge graphs in clinical, biomedical, and translational science

DR Unni, SAT Moxon, M Bada, M Brush… - Clinical and …, 2022 - Wiley Online Library
Within clinical, biomedical, and translational science, an increasing number of projects are
adopting graphs for knowledge representation. Graph‐based data models elucidate the …

Human housekeeping genes are compact

E Eisenberg, EY Levanon - TRENDS in Genetics, 2003 - cell.com
We identify a set of 575 human genes that are expressed in all conditions tested in a publicly
available database of microarray results. Based on this common occurrence, the set is …

[HTML][HTML] Information fusion as an integrative cross-cutting enabler to achieve robust, explainable, and trustworthy medical artificial intelligence

A Holzinger, M Dehmer, F Emmert-Streib, R Cucchiara… - Information …, 2022 - Elsevier
Medical artificial intelligence (AI) systems have been remarkably successful, even
outperforming human performance at certain tasks. There is no doubt that AI is important to …

A deep-learning system bridging molecule structure and biomedical text with comprehension comparable to human professionals

Z Zeng, Y Yao, Z Liu, M Sun - Nature communications, 2022 - nature.com
To accelerate biomedical research process, deep-learning systems are developed to
automatically acquire knowledge about molecule entities by reading large-scale biomedical …

The SARS-CoV-2 RNA Interactome

S Lee, Y Lee, Y Choi, A Son, Y Park, KM Lee, J Kim… - Molecular Cell, 2021 - cell.com
SARS-CoV-2 is an RNA virus whose success as a pathogen relies on its abilities to
repurpose host RNA-binding proteins (RBPs) and to evade antiviral RBPs. To uncover the …

Cytoscape: software for visualization and analysis of biological networks

M Kohl, S Wiese, B Warscheid - Data mining in proteomics: from standards …, 2011 - Springer
Substantial progress has been made in the field of “omics” research (eg, Genomics,
Transcriptomics, Proteomics, and Metabolomics), leading to a vast amount of biological …

Cytoscape: a software environment for integrated models of biomolecular interaction networks

P Shannon, A Markiel, O Ozier, NS Baliga… - Genome …, 2003 - genome.cshlp.org
Cytoscape is an open source software project for integrating biomolecular interaction
networks with high-throughput expression data and other molecular states into a unified …

OrthoMCL: identification of ortholog groups for eukaryotic genomes

L Li, CJ Stoeckert, DS Roos - Genome research, 2003 - genome.cshlp.org
The identification of orthologous groups is useful for genome annotation, studies on
gene/protein evolution, comparative genomics, and the identification of taxonomically …

[HTML][HTML] Prediction of mammalian microRNA targets

BP Lewis, I Shih, MW Jones-Rhoades, DP Bartel… - Cell, 2003 - cell.com
MicroRNAs (miRNAs) can play important gene regulatory roles in nematodes, insects, and
plants by basepairing to mRNAs to specify posttranscriptional repression of these …

The Gene Ontology (GO) database and informatics resource

Gene Ontology Consortium - Nucleic acids research, 2004 - academic.oup.com
Abstract The Gene Ontology (GO) project (http://www. geneontology. org/) provides
structured, controlled vocabularies and classifications that cover several domains of …