Understanding the function of oral mucosal epithelial barriers is essential for a plethora of
research fields such as tumor biology, inflammation and infection diseases, microbiomics …

Primary mucosal melanoma of the oral cavity is an exceedingly rare neoplasm which is
estimated to comprise 1-2% of all oral malignancies. In contrast to cutaneous melanomas …

Melanoma, the tumor arising from the malignant transformation of pigment-producing cells—
the melanocytes—represents one of the most severe cancer types. Despite their rarity …

Abstract Background Mucosal Melanomas (MM) are highly aggressive neoplasms arising
from mucosal melanocytes. Current treatments offer a limited survival benefit for patients …

Oral mucosal melanoma is a relatively rare malignancy with an aggressive clinico-
pathological behaviour. The mean 5-year survival rate is about 15%. It arises primarily from …

Oral mucosal melanomas (OMMs) are aggressive neoplasms commonly found in dogs but
rare in humans. Utilizing whole exome sequencing (WES), which focuses on protein-coding …

Primary oral melanomas are uncommon malignant neoplasm of melanocytes origin. The
most common site of oral melanoma is maxillary gingiva and hard palate. Oral mucosal …

Objectives Mucosal melanomas (MM) are aggressive subtypes of common melanomas. It
remains unclear whether limitations in their resectability or their distinctive molecular …

Mucosal melanoma (MM) is a deadly cancer derived from mucosal melanocytes. To test the
consequences of MM genetics, we developed a zebrafish model in which all melanocytes …

Simple Summary Melanoma is one of the most aggressive cancers in humans, with high
rates of metastasis and a poor prognosis. Because of its environmental, biological and …