Interaction of microglia and astrocytes in the neurovascular unit

L Liu, J Liu, J Bao, Q Bai, G Wang - Frontiers in immunology, 2020 - frontiersin.org
The interaction between microglia and astrocytes significantly influences neuroinflammation.
Microglia/astrocytes, part of the neurovascular unit (NVU), are activated by various brain …

Physiology of astroglia

A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

The “neuro-glial-vascular” unit: the role of glia in neurovascular unit formation and dysfunction

EC Kugler, J Greenwood… - Frontiers in Cell and …, 2021 - frontiersin.org
The neurovascular unit (NVU) is a complex multi-cellular structure consisting of endothelial
cells (ECs), neurons, glia, smooth muscle cells (SMCs), and pericytes. Each component is …

G-protein-coupled receptors in astrocyte–neuron communication

P Kofuji, A Araque - Neuroscience, 2021 - Elsevier
Astrocytes, a major type of glial cell, are known to play key supportive roles in brain function,
contributing to ion and neurotransmitter homeostasis, maintaining the blood–brain barrier …

The neurovascular unit–concept review

V Muoio, PB Persson, MM Sendeski - Acta physiologica, 2014 - Wiley Online Library
The cerebral hyperaemia is one of the fundamental mechanisms for the central nervous
system homeostasis. Due also to this mechanism, oxygen and nutrients are maintained in …

Gamma entrainment: impact on neurocircuits, glia, and therapeutic opportunities

C Adaikkan, LH Tsai - Trends in Neurosciences, 2020 - cell.com
Studies have shown that gamma oscillations (30–100 Hz) are relevant for neurocircuit
function, behavior, and memory. To examine a possible causal contribution of gamma …

[HTML][HTML] Direct vascular contact is a hallmark of cerebral astrocytes

L Hösli, M Zuend, G Bredell, HS Zanker… - Cell reports, 2022 - cell.com
Astrocytes establish extensive networks via gap junctions that allow each astrocyte to
connect indirectly to the vasculature. However, the proportion of astrocytes directly …

Functions of p38 MAP kinases in the central nervous system

PR Asih, E Prikas, K Stefanoska, ARP Tan… - Frontiers in molecular …, 2020 - frontiersin.org
Mitogen-activated protein (MAP) kinases are a central component in signaling networks in a
multitude of mammalian cell types. This review covers recent advances on specific functions …

Emerging evidence for astrocyte dysfunction in schizophrenia

EC de Oliveira Figueiredo, C Calì, F Petrelli, P Bezzi - Glia, 2022 - Wiley Online Library
Schizophrenia is a complex, chronic mental health disorder whose heterogeneous genetic
and neurobiological background influences early brain development, and whose precise …

Astrocytes contribute to gamma oscillations and recognition memory

HS Lee, A Ghetti, A Pinto-Duarte… - Proceedings of the …, 2014 - National Acad Sciences
Glial cells are an integral part of functional communication in the brain. Here we show that
astrocytes contribute to the fast dynamics of neural circuits that underlie normal cognitive …