In order to maintain shape and withstand intracellular pressure, most bacteria are
surrounded by a cell wall that consists mainly of the cross-linked polymer peptidoglycan …

The monofunctional penicillin-binding dd-peptidases and penicillin-hydrolyzing serine β-
lactamases diverged from a common ancestor by the acquisition of structural changes in the …

Bacterial cell division and daughter cell formation are complex mechanisms whose details
are orchestrated by at least a dozen different proteins. Penicillin-binding proteins (PBPs) …

Work on two diverse rod-shaped bacteria, Escherichia coli and Bacillus subtilis, has defined
a set of about 10 conserved proteins that are important for cell division in a wide range of …

During growth and propagation, a bacterial cell enlarges and subsequently divides its
peptidoglycan (PG) sacculus, a continuous mesh‐like layer that encases the cell membrane …

Rod-shaped bacteria grow by adding material into their cell wall via the action of two
spatially distinct enzymatic systems: the Rod complex moves around the cell circumference …

The composition and fine structure of the vegetative cell wall peptidoglycan from Bacillus
subtilis were determined by analysis of its constituent muropeptides. The structures of 39 …

The penicillin-binding proteins (PBPs) polymerize and modify peptidoglycan, the stress-
bearing component of the bacterial cell wall. As part of this process, the PBPs help to create …

Although general physiological functions have been ascribed to the high-molecular-weight
penicillin binding proteins (PBPs) of Escherichia coli, the low-molecular-weight PBPs have …

Bacillus subtilis is the best described member of the Gram positive bacteria. It is a typical rod
shaped bacterium and grows by elongation in its long axis, before dividing at mid cell to …