Adalimumab, ustekinumab, and secukinumab in the management of hidradenitis suppurativa: a review of the real-life experience

F Martora, M Megna, T Battista, L Potestio… - Clinical, Cosmetic …, 2023 - Taylor & Francis
To date, adalimumab (ADA) is the only biotechnology drug approved for the management of
hidradenitis suppurativa (HS), an inflammatory skin condition. However, it quickly became …

Cytokine storm and mucus hypersecretion in COVID-19: review of mechanisms

MA Khan, ZA Khan, M Charles, P Pratap… - Journal of …, 2021 - Taylor & Francis
Mucus is an integral part of the respiratory physiology. It protects the respiratory tract by
acting as a physical barrier against inhaled particles and microbes. Excessive inflammation …

A review of the safety of interleukin-17A inhibitor secukinumab

V Eshwar, A Kamath, R Shastry, AK Shenoy, P Kamath - Pharmaceuticals, 2022 - mdpi.com
Secukinumab is an anti-interleukin (IL)-17A IgG1-κ monoclonal antibody approved for
psoriasis, psoriatic arthritis, and ankylosing spondylitis. Its efficacy is well documented, but …

Assessment of safety profile of secukinumab in real-world scenario using United States food and drug administration adverse event reporting system database

V Eshwar, A Kamath - Scientific Reports, 2024 - nature.com
Secukinumab is an anti-IL-17 monoclonal antibody approved for treating psoriasis and
various arthritides. A comprehensive evaluation of its safety, especially in a real-world …

Paradoxical phenomena of bullous pemphigoid induced and treated by identical biologics

J Zhang, SH Wang, YG Zuo - Frontiers in Immunology, 2023 - frontiersin.org
Objective This study aimed to investigate the clinical features of biologics-induced bullous
pemphigoid (BP) and the therapeutic effects of those agents for BP, exploring the underlying …

Treatment options for juvenile Pityriasis Rubra pilaris

J Guenther, D Novack, S Kamath, S Worswick - Pediatric Drugs, 2023 - Springer
Pityriasis rubra pilaris represents a group of familial and acquired disorders of cornification
that affect both adult and pediatric patients. Treatment options are difficult to assess through …

Allergic contact cell-mediated hypersensitivity in psoriasis: a narrative minireview

AMA Stănescu, AMA Cristea, GC Bejan, M Vieru… - Medicina, 2022 - mdpi.com
The dysfunctionality of the protective skin barrier in psoriasis allows easier cutaneous
penetration of various contact haptens; thus, such patients can develop allergic contact …

The evolving landscape of cutaneous sarcoidosis: pathogenic insight, clinical challenges, and new frontiers in therapy

JH Wu, S Imadojemu, AS Caplan - American Journal of Clinical …, 2022 - Springer
Sarcoidosis is a multisystem disorder of unknown etiology characterized by accumulation of
granulomas in affected tissue. Cutaneous manifestations are among the most common …

[HTML][HTML] Therapies for hidradenitis suppurativa: a systematic review with a focus on Brazil

MC Rivitti-Machado, RF Magalhães, RS da Silva… - Drugs in …, 2022 - ncbi.nlm.nih.gov
Background Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease
associated with a significant negative impact on the quality of life of patients. Methods We …

Behçet's Disease, Pathogenesis, Clinical Features, and Treatment Approaches: A Comprehensive Review

S Lavalle, S Caruso, R Foti, C Gagliano, S Cocuzza… - Medicina, 2024 - mdpi.com
Behçet's disease is a systemic inflammatory disorder of unknown etiology. The disease
manifests with diverse clinical symptoms, most commonly recurrent oral and genital ulcers …