Intracellular signalling pathways activated by leptin

G Frühbeck - Biochemical Journal, 2006 - portlandpress.com
Leptin is a versatile 16 kDa peptide hormone, with a tertiary structure resembling that of
members of the long-chain helical cytokine family. It is mainly produced by adipocytes in …

Crosstalk between adipokines and myokines in fat browning

A Rodríguez, S Becerril, S Ezquerro… - Acta …, 2017 - Wiley Online Library
Skeletal muscle is the largest organ determining whole‐body insulin sensitivity and
metabolic homoeostasis. Adaptive changes of skeletal muscle in response to physical …

[图书][B] Understanding motivation and emotion

J Reeve - 2024 - books.google.com
Comprehensive reference on the nature of motivation and emotion, thoroughly updated with
the latest research and findings in the field Understanding Motivation and Emotion seeks to …

[图书][B] Understanding nutrition

EN Whitney, SR Rolfes, T Crowe, A Walsh - 2019 - books.google.com
Building upon Ellie Whitney and Sharon Rady Rolfes' classic text, this fourth Australian and
New Zealand edition of Understanding Nutrition is a practical and engaging introduction to …

Neuropeptides and the control of food intake in fish

H Volkoff, LF Canosa, S Unniappan… - General and …, 2005 - Elsevier
The brain, particularly the hypothalamus, integrates input from factors that stimulate
(orexigenic) and inhibit (anorexigenic) food intake. In fish, the identification of appetite …

Leptin: structure, function and biology

F Zhang, Y Chen, M Heiman, R DiMarchi - Vitamins & hormones, 2005 - Elsevier
Leptin is an adipocyte‐derived hormone that acts as a major regulator for food intake and
energy homeostasis. Leptin deficiency or resistance can result in profound obesity, diabetes …

Leptin signaling in the hypothalamus: emphasis on energy homeostasis and leptin resistance

A Sahu - Frontiers in neuroendocrinology, 2003 - Elsevier
Leptin, the long-sought satiety factor of adipocytes origin, has emerged as one of the major
signals that relay the status of fat stores to the hypothalamus and plays a significant role in …

The secretory function of adipocytes in the physiology of white adipose tissue

P Wang, E Mariman, J Renes… - Journal of cellular …, 2008 - Wiley Online Library
White adipose tissue, previously regarded as a passive lipid storage site, is now viewed as a
dynamic tissue. It has the capacity to actively communicate by sending and receiving …

Insulin Signaling in the Central Nervous System: A Critical Role in Metabolic Homeostasis and Disease From C. elegans to Humans

D Porte Jr, DG Baskin, MW Schwartz - Diabetes, 2005 - Am Diabetes Assoc
Insulin and its signaling systems are implicated in both central and peripheral mechanisms
governing the ingestion, distribution, metabolism, and storage of nutrients in organisms …

Apelin-13 and apelin-36 exhibit direct cardioprotective activity against ischemiareperfusion injury

JC Simpkin, DM Yellon, SM Davidson, SY Lim… - Basic research in …, 2007 - Springer
Protection against myocardial ischemia-reperfusion (I/R) injury involves activation of
phosphatidylinositol-3-OH kinase (PI3K)-Akt/protein kinase B and p44/42 mitogen-activated …