[HTML][HTML] Porcine reproductive and respiratory syndrome virus reverse genetics and the major applications
J Chaudhari, HLX Vu - Viruses, 2020 - mdpi.com
Porcine reproductive and respiratory syndrome virus (PRRSV) is a positive sense, single-
stranded RNA virus that is known to infect only pigs. The virus emerged in the late 1980s …
stranded RNA virus that is known to infect only pigs. The virus emerged in the late 1980s …
[HTML][HTML] Porcine reproductive and respiratory syndrome virus: immune escape and application of reverse genetics in attenuated live vaccine development
H Wang, Y Xu, W Feng - Vaccines, 2021 - mdpi.com
Porcine reproductive and respiratory syndrome virus (PRRSV), an RNA virus widely
prevalent in pigs, results in significant economic losses worldwide. PRRSV can escape from …
prevalent in pigs, results in significant economic losses worldwide. PRRSV can escape from …
Efficacy of a porcine reproductive and respiratory syndrome virus 1 (PRRSV-1) natural recombinant against a heterologous PRRSV-1 isolate both clustered within the …
C Li, S Li, S Li, M Qiu, H Lin, Z Sun, Y Qiu, W Qi… - Veterinary …, 2023 - Elsevier
Porcine reproductive and respiratory syndrome virus 1 (PRRSV-1) has been prevalent in
more than 20 provinces of China. However, no PRRSV-1-specific vaccine is commercially …
more than 20 provinces of China. However, no PRRSV-1-specific vaccine is commercially …
Strategies to broaden the cross-protective efficacy of vaccines against porcine reproductive and respiratory syndrome virus
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most
economically important viral pathogens currently affecting swine production worldwide …
economically important viral pathogens currently affecting swine production worldwide …
[HTML][HTML] Chimeric HP-PRRSV2 containing an ORF2-6 consensus sequence induces antibodies with broadly neutralizing activity and confers cross protection against …
N Chen, S Li, Y Tian, X Li, S Li, J Li, M Qiu, Z Sun… - Veterinary …, 2021 - Springer
Due to the substantial genetic diversity of porcine reproductive and respiratory syndrome
virus (PRRSV), commercial PRRS vaccines fail to provide sufficient cross protection …
virus (PRRSV), commercial PRRS vaccines fail to provide sufficient cross protection …
Recombinant porcine reproductive and respiratory syndrome virus expressing membrane-bound interleukin-15 as an immunomodulatory adjuvant enhances NK and …
Cytokines are often used as adjuvants to improve vaccine immunogenicity, since they are
important in initiating and shaping the immune response. The available commercial …
important in initiating and shaping the immune response. The available commercial …
Enhancing heterologous protection in pigs vaccinated with chimeric porcine reproductive and respiratory syndrome virus containing the full-length sequences of …
D Tian, D Cao, CL Heffron, DM Yugo, AJ Rogers… - Vaccine, 2017 - Elsevier
Porcine reproductive and respiratory syndrome virus (PRRSV) is the causative agent of
arguably the most economically important global swine disease. The extensive genetic …
arguably the most economically important global swine disease. The extensive genetic …
[HTML][HTML] A PRRSV GP5-Mosaic vaccine: Protection of pigs from challenge and ex vivo detection of IFNγ responses against several genotype 2 strains
J Cui, CM O'Connell, A Costa, Y Pan, JA Smyth… - PLoS …, 2019 - journals.plos.org
Porcine reproductive and respiratory syndrome virus (PRRSV), is a highly mutable RNA
virus that affects swine worldwide and its control is very challenging due to its formidable …
virus that affects swine worldwide and its control is very challenging due to its formidable …
[HTML][HTML] A chimeric virus created by DNA shuffling of the capsid genes of different subtypes of porcine circovirus type 2 (PCV2) in the backbone of the non-pathogenic …
Abstract Porcine circovirus type 2 (PCV2) is the primary causative agent of porcine circovirus-
associated disease (PCVAD). Available commercial vaccines all target PCV2a subtype …
associated disease (PCVAD). Available commercial vaccines all target PCV2a subtype …
[HTML][HTML] The non-structural protein Nsp2TF of porcine reproductive and respiratory syndrome virus down-regulates the expression of Swine Leukocyte Antigen class I
Porcine reproductive and respiratory syndrome virus (PRRSV) is arguably the most
economically-important global swine pathogen. Here we demonstrated that PRRSV down …
economically-important global swine pathogen. Here we demonstrated that PRRSV down …