Understanding the role of the gut microbiome and microbial metabolites in non-alcoholic fatty liver disease: current evidence and perspectives

N Vallianou, GS Christodoulatos, I Karampela… - Biomolecules, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide. NAFLD begins as a relatively benign hepatic steatosis which can evolve to non …

Prebiotics: definition, types, sources, mechanisms, and clinical applications

D Davani-Davari, M Negahdaripour, I Karimzadeh… - Foods, 2019 - mdpi.com
Prebiotics are a group of nutrients that are degraded by gut microbiota. Their relationship
with human overall health has been an area of increasing interest in recent years. They can …

Intestinal microbiota-derived short chain fatty acids in host health and disease

J Cong, P Zhou, R Zhang - Nutrients, 2022 - mdpi.com
Intestinal microbiota has its role as an important component of human physiology. It
produces metabolites that module key functions to establish a symbiotic crosstalk with their …

The short-chain fatty acid acetate in body weight control and insulin sensitivity

MA González Hernández, EE Canfora, JWE Jocken… - Nutrients, 2019 - mdpi.com
The interplay of gut microbiota, host metabolism, and metabolic health has gained increased
attention. Gut microbiota may play a regulatory role in gastrointestinal health, substrate …

Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism

DJ Morrison, T Preston - Gut microbes, 2016 - Taylor & Francis
The formation of SCFA is the result of a complex interplay between diet and the gut
microbiota within the gut lumen environment. The discovery of receptors, across a range of …

[HTML][HTML] Circulating but not faecal short-chain fatty acids are related to insulin sensitivity, lipolysis and GLP-1 concentrations in humans

M Müller, MAG Hernández, GH Goossens… - Scientific Reports, 2019 - nature.com
Microbial-derived short-chain fatty acids (SCFA) acetate, propionate and butyrate may
provide a link between gut microbiota and whole-body insulin sensitivity (IS). In this cross …

Short-chain fatty acids in control of body weight and insulin sensitivity

EE Canfora, JW Jocken, EE Blaak - Nature Reviews Endocrinology, 2015 - nature.com
The connection between the gut microbiota and the aetiology of obesity and cardiometabolic
disorders is increasingly being recognized by clinicians. Our gut microbiota might affect the …

Short chain fatty acids: key regulators of the local and systemic immune response in inflammatory diseases and infections

LM Ney, M Wipplinger, M Grossmann… - Open …, 2023 - royalsocietypublishing.org
The human intestinal microbiome substantially affects human health and resistance to
infections in its dynamic composition and varying release of microbial-derived metabolites …

Dietary gut microbial metabolites, short-chain fatty acids, and host metabolic regulation

M Kasubuchi, S Hasegawa, T Hiramatsu, A Ichimura… - Nutrients, 2015 - mdpi.com
During feeding, the gut microbiota contributes to the host energy acquisition and metabolic
regulation thereby influencing the development of metabolic disorders such as obesity and …

The gut microbiome in hypertension: recent advances and future perspectives

EG Avery, H Bartolomaeus, A Maifeld, L Marko… - Circulation …, 2021 - Am Heart Assoc
The pathogenesis of hypertension is known to involve a diverse range of contributing factors
including genetic, environmental, hormonal, hemodynamic and inflammatory forces, to …