Deciphering miRNAs' action through miRNA editing

M Correia de Sousa, M Gjorgjieva, D Dolicka… - International journal of …, 2019 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs with the capability of modulating gene
expression at the post-transcriptional level either by inhibiting messenger RNA (mRNA) …

Regulatory role of microRNAs (miRNAs) in the recent development of abiotic stress tolerance of plants

Y Begum - Gene, 2022 - Elsevier
MicroRNAs (miRNAs) are a distinct groups of single-stranded non-coding, tiny regulatory
RNAs approximately 20–24 nucleotides in length. miRNAs negatively influence gene …

MirGeneDB 2.1: toward a complete sampling of all major animal phyla

B Fromm, E Høye, D Domanska, X Zhong… - Nucleic acids …, 2022 - academic.oup.com
We describe an update of MirGeneDB, the manually curated microRNA gene database.
Adhering to uniform and consistent criteria for microRNA annotation and nomenclature, we …

Functional enrichment analysis of regulatory elements

A Garcia-Moreno, R López-Domínguez… - Biomedicines, 2022 - mdpi.com
Statistical methods for enrichment analysis are important tools to extract biological
information from omics experiments. Although these methods have been widely used for the …

MirGeneDB 2.0: the metazoan microRNA complement

B Fromm, D Domanska, E Høye… - Nucleic Acids …, 2020 - academic.oup.com
Small non-coding RNAs have gained substantial attention due to their roles in animal
development and human disorders. Among them, microRNAs are special because …

DIANA-miTED: a microRNA tissue expression database

I Kavakiotis, A Alexiou, S Tastsoglou… - Nucleic Acids …, 2022 - academic.oup.com
Abstract microRNAs (miRNAs) are short (∼ 23nt) single-stranded non-coding RNAs that act
as potent post-transcriptional gene expression regulators. Information about miRNA …

T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles

PF Céspedes, A Jainarayanan… - Nature …, 2022 - nature.com
The immunological synapse is a molecular hub that facilitates the delivery of three activation
signals, namely antigen, costimulation/corepression and cytokines, from antigen-presenting …

Therapy implications of hepatitis C virus genetic diversity

MA Martinez, S Franco - Viruses, 2020 - mdpi.com
Hepatitis C virus (HCV) is an important human pathogen with a high chronicity rate. An
estimated 71 million people worldwide are living with chronic hepatitis C (CHC) infection …

ALL-tRNAseq enables robust tRNA profiling in tissue samples

C Scheepbouwer, E Aparicio-Puerta… - Genes & …, 2023 - genesdev.cshlp.org
Transfer RNAs (tRNAs) are small adaptor RNAs essential for mRNA translation. Alterations
in the cellular tRNA population can directly affect mRNA decoding rates and translational …

miRNAs as biomarkers in diabetes: moving towards precision medicine

MA Angelescu, O Andronic, SO Dima… - International Journal of …, 2022 - mdpi.com
Diabetes mellitus (DM) is a complex metabolic disease with many specifically related
complications. Early diagnosis of this disease could prevent the progression to overt disease …