Betulin and betulinic acid: Triterpenoids derivatives with a powerful biological potential
A Hordyjewska, A Ostapiuk, A Horecka… - Phytochemistry …, 2019 - Springer
Betulin, a pentacyclic triterpene and a plant pentacyclic triterpene metabolite, can be found
in large quantities in the outer bark of the birches (Betula, Betulaceae). Betulinic acid …
in large quantities in the outer bark of the birches (Betula, Betulaceae). Betulinic acid …
Betulin and its derivatives as novel compounds with different pharmacological effects
Betulin (B) and Betulinic acid (BA) are natural pentacyclic lupane-structure triterpenoids
which possess a wide range of pharmacological activities. Recent evidence indicates that B …
which possess a wide range of pharmacological activities. Recent evidence indicates that B …
Ursolic acid and its derivatives as bioactive agents
Non-communicable diseases (NCDs) such as cancer, diabetes, and chronic respiratory and
cardiovascular diseases continue to be threatening and deadly to human kind. Resistance …
cardiovascular diseases continue to be threatening and deadly to human kind. Resistance …
Ursolic acid-based derivatives as potential anti-cancer agents: An update
Ursolic acid is a pharmacologically active pentacyclic triterpenoid derived from medicinal
plants, fruit, and vegetables. The pharmacological activities of ursolic acid have been …
plants, fruit, and vegetables. The pharmacological activities of ursolic acid have been …
Ursolic acid (UA): A metabolite with promising therapeutic potential
Plants are known to produce a variety of bioactive metabolites which are being used to cure
various life threatening and chronic diseases. The molecular mechanism of action of such …
various life threatening and chronic diseases. The molecular mechanism of action of such …
Terpenoids as potential geroprotectors
E Proshkina, S Plyusnin, T Babak, E Lashmanova… - Antioxidants, 2020 - mdpi.com
Terpenes and terpenoids are the largest groups of plant secondary metabolites. However,
unlike polyphenols, they are rarely associated with geroprotective properties. Here we …
unlike polyphenols, they are rarely associated with geroprotective properties. Here we …
Targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids: Potential role in prevention and therapy of cancer
MK Shanmugam, AH Nguyen, AP Kumar, BKH Tan… - Cancer letters, 2012 - Elsevier
Over the last two decades, extensive research on plant-based medicinal compounds has
revealed exciting and important pharmacological properties and activities of triterpenoids …
revealed exciting and important pharmacological properties and activities of triterpenoids …
The possible role of ursolic acid in Covid-19: a real game changer
HM Al-Kuraishy, AI Al-Gareeb, GES Batiha - Clinical nutrition ESPEN, 2022 - Elsevier
Ursolic acid (UA) is a pentacyclic terpenoid is usually found in the fruit peels and stem bark
as secondary metabolites. UA has antiviral, antibacterial, and antiparasitic properties. UA …
as secondary metabolites. UA has antiviral, antibacterial, and antiparasitic properties. UA …
Ursolic acid and SARS-CoV-2 infection: a new horizon and perspective
Abstract SARS-CoV-2 (severe acute respiratory syndrome coronavirus type 2) has been
identified as the source of a world coronavirus pandemic in 2019. Covid-19 is considered a …
identified as the source of a world coronavirus pandemic in 2019. Covid-19 is considered a …
Cheminformatics-based study identifies potential ebola VP40 inhibitors
The Ebola virus (EBOV) is still highly infectious and causes severe hemorrhagic fevers in
primates. However, there are no regulatorily approved drugs against the Ebola virus disease …
primates. However, there are no regulatorily approved drugs against the Ebola virus disease …