Background Microbiological confirmation of childhood tuberculosis is rare because of the
difficulty of collection of specimens, low sensitivity of smear microscopy, and poor access to …

Background Every year, at least one million children become ill with tuberculosis and
around 200,000 children die. Xpert MTB/RIF and Xpert Ultra are World Health Organization …

Pulmonary tuberculosis still remains a major communicable disease worldwide. In 2013, 9
million people developed TB and 1.5 million people died from the disease. India constitutes …

Background In children admitted to hospital, rapid, accurate diagnosis of pulmonary
tuberculosis with the Xpert MTB/RIF assay is possible, but no paediatric studies have been …

Background Rapid detection of rifampicin resistance is essential for early management and
prevention of transmission of multidrug-resistant tuberculosis (MDR-TB). We studied the …

Objective To determine the sensitivity and specificity of a Computer Aided Diagnosis (CAD)
program for scoring chest x-rays (CXRs) of presumptive tuberculosis (TB) patients compared …

Objectives The WHO currently recommends stool testing using GeneXpert MTB/Rif (Xpert)
for the diagnosis of paediatric tuberculosis (TB). The simple one-step (SOS) stool method …

Technological advances in nucleic acid amplification have led to breakthroughs in the early
detection of PTB compared to traditional sputum smear tests. The sensitivity and specificity …

Background Tuberculosis (TB) in children is neglected, mainly due to lack of sensitive
diagnostic tools. Recently Xpert MTB/RIF assay has revolutionized the diagnostic field, but …

Introduction As studies of biomarkers of tuberculosis (TB) disease provide hope for a simple,
point-of-care test, we aimed to synthesize evidence on biomarkers for diagnosis of TB in …