Maintenance of a homeostatic body core temperature is a critical brain function
accomplished by a central neural network. This orchestrates a complex behavioral and …

Various environmental stressors, such as extreme temperatures (hot and cold), pathogens,
predators and insufficient food, can threaten life. Remarkable progress has recently been …

Central neural circuits orchestrate a homeostatic repertoire to maintain body temperature
during environmental temperature challenges and to alter body temperature during the …

Body temperature regulation is a fundamental homeostatic function that is governed by the
central nervous system in homeothermic animals, including humans. The central …

Systemic inflammation-associated syndromes (eg, sepsis and septic shock) often have high
mortality and remain a challenge in emergency medicine. Systemic inflammation is usually …

Brown adipose tissue (BAT) is a specialized organ responsible for thermogenesis, a process
required for maintaining body temperature. BAT is regulated by the sympathetic nervous …

Thermogenesis, the production of heat energy, is an essential component of the homeostatic
repertoire to maintain body temperature during the challenge of low environmental …

Thermogenesis, the production of heat energy, in brown adipose tissue is a significant
component of the homeostatic repertoire to maintain body temperature during the challenge …

Brown adipose tissue (BAT) is a specialized tissue critical for non-shivering thermogenesis
producing heat through mitochondrial uncoupling; whereas white adipose tissue (WAT) is …

The bidirectional controller of the thermoregulatory center in the preoptic area (POA) is
unknown. Using rats, here, we identify prostaglandin EP3 receptor–expressing POA …