Recent developments in the design of functional derivatives of edaravone and exploration of their antioxidant activities

RD Mohan, NV Kulkarni - Molecular Diversity, 2024 - Springer
Edaravone, a pyrazalone derivative, is an antioxidant and free radical scavenger used to
treat oxidative stress-related diseases. It is a proven drug to mitigate conditions prevailing to …

Transition-metal-free direct arylselenation of 1-aryl-3-methyl pyrazolones using diselenides

VD Prajapati, RV Prajapati, VB Purohit, LA Baptista… - Tetrahedron, 2024 - Elsevier
A novel approach for the direct selenation of 1-arylpyrazolones has been described using
diselenides as the selenating reagent. The protocol was found to be simple and efficient to …

N‐Chlorosuccinimide Mediated Direct C−H Thiocyanation of 1‐Aryl‐5‐pyrazolones at Room Temperature

RV Prajapati, VD Prajapati, VB Purohit… - …, 2023 - Wiley Online Library
A facile synthetic protocol has been established for the N‐chlorosuccinimide (NCS)
promoted direct C− H thiocyanation of 1‐aryl‐5‐pyrazolones via in situ‐generated …

I2/DMSO-mediated C (sp2)-S bond formation between heterocyclic enamines and triethylammonium thiolates

W Fan - Tetrahedron, 2023 - Elsevier
An efficient I 2/DMSO-mediated oxidative dehydrogenative coupling reaction between
heterocyclic enamines and triethylammonium thiolates under microwave conditions is …