Background: Previous guidelines for the management of thyroid nodules and cancers were
geared toward adults. Compared with thyroid neoplasms in adults, however, those in the …

Thyroid cancer is rare in the pediatric population, but thyroid carcinomas occurring in
children carry a unique set of clinical, pathologic, and molecular characteristics. In …

Context The specific characteristics of pediatric and adolescent differentiated thyroid cancer
(DTC) is the more frequent occurrence of distant metastasis (DM) compared with adult DTC …

Background The aim of this study was to analyze the clinical features and clinical outcomes
of papillary thyroid carcinoma (PTC) in the pediatric and adolescent population treated in …

Sorafenib (Nexavar) is a multikinase inhibitor, which has demonstrated both anti-
proliferative and anti-angiogenic properties in vitro and in vivo, inhibiting the activity of …

Abstract Background Differentiated thyroid carcinomas (DTCs) are rare in young children but
represent almost 10% of all malignancies diagnosed in older adolescents. Methods This …

Background: Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy in
children and adolescents. Infrequently, children with PTC may present with or develop …

Differentiated thyroid carcinoma (DTC) is the most common malignant neoplasm of the
endocrine system. In children and adolescents, DTC usually presents as a more aggressive …

Differentiated thyroid cancer (DTC) is the most common childhood thyroid malignancy. The
standard of care for pediatric DTC is total thyroidectomy followed by radioactive iodine (RAI) …

Introduction: Sorafenib (Nexavar) is an oral multi-kinase inhibitor targeting B-type Raf kinase
(BRAF)(both wild type and BRAFV600E), VEGFR1, VEGFR2, VEGFR3, PDGFRβ and RET …