[HTML][HTML] The role of non-coding RNAs in oncology
FJ Slack, AM Chinnaiyan - Cell, 2019 - cell.com
For decades, research into cancer biology focused on the involvement of protein-coding
genes. Only recently was it discovered that an entire class of molecules, termed non-coding …
genes. Only recently was it discovered that an entire class of molecules, termed non-coding …
[HTML][HTML] The role and mechanisms of action of microRNAs in cancer drug resistance
W Si, J Shen, H Zheng, W Fan - Clinical epigenetics, 2019 - Springer
MicroRNAs (miRNAs) are small non-coding RNAs with a length of about 19–25 nt, which
can regulate various target genes and are thus involved in the regulation of a variety of …
can regulate various target genes and are thus involved in the regulation of a variety of …
MicroRNA in lung cancer: role, mechanisms, pathways and therapeutic relevance
Lung cancer is the cardinal cause of cancer-related deaths with restricted recourse of
therapy throughout the world. Clinical success of therapies is not very promising due to-late …
therapy throughout the world. Clinical success of therapies is not very promising due to-late …
miRNAs in lung cancer. A systematic review identifies predictive and prognostic miRNA candidates for precision medicine in lung cancer
S Zhong, H Golpon, P Zardo, J Borlak - Translational Research, 2021 - Elsevier
Lung cancer (LC) is the leading cause of cancer-related death worldwide and miRNAs play
a key role in LC development. To better diagnose LC and to predict drug treatment …
a key role in LC development. To better diagnose LC and to predict drug treatment …
[HTML][HTML] MicroRNA and cancer
MD Jansson, AH Lund - Molecular oncology, 2012 - Elsevier
With the advent of next generation sequencing techniques a previously unknown world of
non-coding RNA molecules have been discovered. Non-coding RNA transcripts likely …
non-coding RNA molecules have been discovered. Non-coding RNA transcripts likely …
[HTML][HTML] Functions of lncRNA HOTAIR in lung cancer
G Loewen, J Jayawickramarajah, Y Zhuo… - Journal of hematology & …, 2014 - Springer
Long non-coding RNAs (lncRNAs) govern fundamental biochemical and cellular processes.
lncRNA HOX transcript antisense RNA (HOTAIR) represses gene expression through …
lncRNA HOX transcript antisense RNA (HOTAIR) represses gene expression through …
[HTML][HTML] Mir-34: a new weapon against cancer?
The microRNA (miRNA)-34a is a key regulator of tumor suppression. It controls the
expression of a plethora of target proteins involved in cell cycle, differentiation and …
expression of a plethora of target proteins involved in cell cycle, differentiation and …
[HTML][HTML] miR-34–a microRNA replacement therapy is headed to the clinic
AG Bader - Frontiers in genetics, 2012 - frontiersin.org
MicroRNA-34 (miR-34) is a master regulator of tumor suppression. It is downregulated in
numerous cancers and inhibits malignant growth by repressing genes involved in various …
numerous cancers and inhibits malignant growth by repressing genes involved in various …
[HTML][HTML] MiRNA as potential biomarkers and therapeutic targets for gastric cancer
VY Shin, KM Chu - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Gastric cancer is one of the leading causes of cancer mortality in the world. Aberrant
expression of microRNAs (miRNAs) is the hallmark of this disease. MiRNAs are …
expression of microRNAs (miRNAs) is the hallmark of this disease. MiRNAs are …
MicroRNAs in the p53 network: micromanagement of tumour suppression
H Hermeking - Nature reviews cancer, 2012 - nature.com
In recent years, microRNAs (miRNAs) have been identified as mediators of tumour
suppression and stress responses exerted by the p53 tumour suppressor. p53-regulated …
suppression and stress responses exerted by the p53 tumour suppressor. p53-regulated …