Structural and (pseudo-) enzymatic properties of neuroglobin: Its possible role in neuroprotection

G De Simone, D Sbardella, F Oddone, A Pesce… - Cells, 2021 - mdpi.com
Neuroglobin (Ngb), the third member of the globin family, was discovered in human and
murine brains in 2000. This monomeric globin is structurally similar to myoglobin (Mb) and …

A functional genetic screen for metabolic proteins unveils GART and the de novo purine biosynthetic pathway as novel targets for the treatment of luminal A ERα …

M Cipolletti, S Leone, S Bartoloni… - Frontiers in …, 2023 - frontiersin.org
Targeting tumor cell metabolism is a new frontier in cancer management. Thus, metabolic
pathway inhibitors could be used as anti-estrogen receptor α (ERα) breast cancer (BC) …

[HTML][HTML] Neuroglobin-enriched secretome provides neuroprotection against hydrogen peroxide and mitochondrial toxin-induced cellular stress

G Bastari, VS Fernandez, M Muzzi, S Moreno… - Cell …, 2024 - pmc.ncbi.nlm.nih.gov
Aberrant response to physiological cell stress is part of the mechanisms underlying the
development of diverse human diseases, including neuropathologies. Neuroglobin (NGB) …

Editorial for Special Issue: Neuroglobin from Brain Protection to Cancer Progression

M Marino, R Misasi, M Ruoppolo - Cells, 2022 - mdpi.com
Since its discovery in 2000 [1] and characterization of its preferential expression in the brain
[1, 2], neuroglobin (NGB) presented a new opportunity to understand the mechanisms …

[PDF][PDF] Action of Estrogen In Breast Cancer: A review Study

S Ibrahim, R Berkson - Kufa Journal for Nursing Sciences, 2022 - iasj.net
Estrogen hormone is one of the steroid hormones has a critical role in breast cancer
etiology. It has been implicated in proliferation and differentiation of cells through its action …

[PDF][PDF] Structural and (Pseudo-) Enzymatic Properties of Neuroglobin: Its Possible Role in Neuroprotection. Cells 2021, 10, 3366

G De Simone, D Sbardella, F Oddone, A Pesce… - 2021 - academia.edu
Neuroglobin (Ngb), the third member of the globin family, was discovered in human and
murine brains in 2000. This monomeric globin is structurally similar to myoglobin (Mb) and …