In many eukaryotes, including mammals, plants, yeast, and insects, introns can increase
gene expression without functioning as a binding site for transcription factors. This …

Pre-mRNA maturation frequently occurs at the same time and place as transcription by RNA
polymerase II. The co-transcriptionality of mRNA processing has permitted the evolution of …

Nuclear proteins are often given a concise title that captures their function, such as
'transcription factor,''polymerase'or 'nuclear-receptor.'However, for members of the …

The vast diversity of cellular types and behaviours is mainly the result of combinatorial
interactions between a limited number of transcription factors and cellular signalling …

Much of the complex process of RNP biogenesis takes place at the gene cotranscriptionally.
The target for RNA binding and processing factors is, therefore, not a solitary RNA molecule …

Extensive research in the past decade has significantly broadened our view about the role
actin plays in the life of the cell and added novel aspects to actin research. One of these new …

Actin participates in several essential processes in the cell nucleus. Even though the
presence of actin in the nucleus was proposed more than 30 years ago, nuclear processes …

The mystery of nuclear actin has puzzled biologists for decades largely due to the lack of
defined experimental systems. However, the development of actin-containing chromatin …

Actin and myosin are major components of the cell cytoskeleton, with structural and
regulatory functions that affect many essential cellular processes. Although they were …

Nuclear actin is involoved in the transcription of all three RNA polymerases, in chromatin
remodeling and in the formation of heterogeneous nuclear ribonucleoprotein complexes, as …