Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV
AM Lambeir, C Durinx, S Scharpé… - Critical reviews in …, 2003 - Taylor & Francis
Dipeptidyl-peptidase IV/CD26 (DPP IV) is a cell-surface protease belonging to the
prolyloligopeptidase family. It selectively removes the N-terminal dipeptide from peptides …
prolyloligopeptidase family. It selectively removes the N-terminal dipeptide from peptides …
[HTML][HTML] Regulation of T cell immunity in atopic dermatitis by microbes: the yin and yang of cutaneous inflammation
T Biedermann, Y Skabytska, S Kaesler… - Frontiers in …, 2015 - frontiersin.org
Atopic dermatitis (AD) is a chronic inflammatory skin disease predominantly mediated by T
helper cells. While numerous adaptive immune mechanisms in AD pathophysiology have …
helper cells. While numerous adaptive immune mechanisms in AD pathophysiology have …
Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical …
M Gobert, I Treilleux, N Bendriss-Vermare, T Bachelot… - Cancer research, 2009 - AACR
Immunohistochemical analysis of FOXP3 in primary breast tumors showed that a high
number of tumor-infiltrating regulatory T cells (Ti-Treg) within lymphoid infiltrates …
number of tumor-infiltrating regulatory T cells (Ti-Treg) within lymphoid infiltrates …
CCL22 controls immunity by promoting regulatory T cell communication with dendritic cells in lymph nodes
M Rapp, MWM Wintergerst, WG Kunz… - Journal of Experimental …, 2019 - rupress.org
Chemokines have crucial roles in organ development and orchestration of leukocyte
migration. The chemokine CCL22 is expressed constitutively at high levels in the lymph …
migration. The chemokine CCL22 is expressed constitutively at high levels in the lymph …
Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids
V Wittamer, JD Franssen, M Vulcano… - The Journal of …, 2003 - rupress.org
Dendritic cells (DCs) and macrophages are professional antigen-presenting cells (APCs)
that play key roles in both innate and adaptive immunity. ChemR23 is an orphan G protein …
that play key roles in both innate and adaptive immunity. ChemR23 is an orphan G protein …
Cell-specific gene expression in Langerhans cell histiocytosis lesions reveals a distinct profile compared with epidermal Langerhans cells
CE Allen, L Li, TL Peters, HE Leung, A Yu… - The Journal of …, 2010 - journals.aai.org
Langerhans cell histiocytosis (LCH) is a rare disease characterized by heterogeneous
lesions containing CD207+ Langerhans cells (LCs) and lymphocytes that can arise in …
lesions containing CD207+ Langerhans cells (LCs) and lymphocytes that can arise in …
Dendritic cells: emerging pharmacological targets of immunosuppressive drugs
H Hackstein, AW Thomson - Nature Reviews Immunology, 2004 - nature.com
Immunosuppressive drugs have revolutionized organ transplantation and improved the
therapeutic management of autoimmune diseases. The development of immunosuppressive …
therapeutic management of autoimmune diseases. The development of immunosuppressive …
CCL17 and CCL22 chemokines within tumor microenvironment are related to accumulation of Foxp3+ regulatory T cells in gastric cancer
Y Mizukami, K Kono, Y Kawaguchi… - … journal of cancer, 2008 - Wiley Online Library
It has been reported that an increased population of regulatory T cells (Tregs) is one of the
reasons for impaired anti‐tumor immunity. Recently, Foxp3 has been reported as a reliable …
reasons for impaired anti‐tumor immunity. Recently, Foxp3 has been reported as a reliable …
[HTML][HTML] Regulatory T cells infiltrate the tumor-induced tertiary lymphoïd structures and are associated with poor clinical outcome in NSCLC
P Devi-Marulkar, S Fastenackels… - Communications …, 2022 - nature.com
On one hand, regulatory T cells (Tregs) play an immunosuppressive activity in most solid
tumors but not all. On the other hand, the organization of tumor-infiltrating immune cells into …
tumors but not all. On the other hand, the organization of tumor-infiltrating immune cells into …
Cross-linking of the mannose receptor on monocyte-derived dendritic cells activates an anti-inflammatory immunosuppressive program
M Chieppa, G Bianchi, A Doni, A Del Prete… - The Journal of …, 2003 - journals.aai.org
Immature monocyte-derived dendritic cells (DC) strongly express the endocytic mannose
receptor (MR). Addition of a specific anti-MR mAb (clone PAM-1) for 24 h to cultures of …
receptor (MR). Addition of a specific anti-MR mAb (clone PAM-1) for 24 h to cultures of …