Monkeypox: disease epidemiology, host immunity and clinical interventions

FM Lum, A Torres-Ruesta, MZ Tay, RTP Lin… - Nature Reviews …, 2022 - nature.com
Monkeypox virus (MPXV), which causes disease in humans, has for many years been
restricted to the African continent, with only a handful of sporadic cases in other parts of the …

[HTML][HTML] Monkeypox: epidemiology, pathogenesis, treatment and prevention

Y Huang, L Mu, W Wang - Signal Transduction and Targeted Therapy, 2022 - nature.com
Monkeypox is a zoonotic disease that was once endemic in west and central Africa caused
by monkeypox virus. However, cases recently have been confirmed in many nonendemic …

[HTML][HTML] Reemergence of human monkeypox and declining population immunity in the context of urbanization, Nigeria, 2017–2020

PY Nguyen, WS Ajisegiri, V Costantino… - Emerging Infectious …, 2021 - ncbi.nlm.nih.gov
A monkeypox outbreak in Nigeria during 2017–2020 provides an illustrative case study for
emerging zoonoses. We built a statistical model to simulate declining immunity from …

When a neglected tropical disease goes global: knowledge, attitudes and practices of Italian physicians towards monkeypox, preliminary results

M Riccò, P Ferraro, V Camisa, E Satta… - Tropical medicine and …, 2022 - mdpi.com
Monkeypox (MPX) has been regarded as a neglected tropic disease of Western and Central
Africa since the early 70s. However, during May 2022, an unprecedent outbreak of MPX has …

Human monkeypox: epidemiologic and clinical characteristics, diagnosis, and prevention

E Petersen, A Kantele, M Koopmans… - Infectious Disease …, 2019 - id.theclinics.com
Human monkeypox virus (MPXV) is a double-stranded DNA virus of the Orthopoxvirus
genus of the family Poxviridae. 1–4 Two genetic clades of the monkeypox virus have been …

An mpox virus mRNA-lipid nanoparticle vaccine confers protection against lethal orthopoxviral challenge

AW Freyn, C Atyeo, PL Earl, JL Americo… - Science translational …, 2023 - science.org
Mpox virus (MPXV) caused a global outbreak in 2022. Although smallpox vaccines were
rapidly deployed to curb spread and disease among those at highest risk, breakthrough …

Clinical characteristics of monkeypox virus infections among men with and without HIV: a large outbreak cohort in Germany

C Hoffmann, H Jessen, C Wyen, S Grunwald… - HIV …, 2023 - Wiley Online Library
Abstract Background Since May 2022, increasing numbers of monkeypox virus (MPXV)
infections have been reported from across Europe and North America. Studies, mainly from …

[HTML][HTML] The virology of human monkeypox virus (hMPXV): A brief overview

E Lansiaux, N Jain, S Laivacuma, A Reinis - Virus research, 2022 - Elsevier
First described in 1958, the human monkeypox virus (hMPXV) is a neglected zoonotic
pathogen closely associated with the smallpox virus. The virus usually spreads via close …

The land-scape of immune response to monkeypox virus

H Li, QZ Huang, H Zhang, ZX Liu, XH Chen, LL Ye… - …, 2023 - thelancet.com
Human monkeypox is a viral zoonotic smallpox-like disease caused by the monkeypox virus
(MPXV) and has become the greatest public health threat in the genus Orthopoxvirus after …

Mpox vaccine and infection-driven human immune signatures: an immunological analysis of an observational study

H Cohn, N Bloom, GY Cai, JJ Clark, A Tarke… - The Lancet Infectious …, 2023 - thelancet.com
Background Monkeypox virus has recently infected more than 88 000 people, raising
concerns about our preparedness against this emerging viral pathogen. Licensed and …