Quercetin attenuates neurotoxicity induced by iron oxide nanoparticles

A Bardestani, S Ebrahimpour, A Esmaeili… - Journal of …, 2021 - Springer
Iron oxide nanoparticles (IONPs) have been proposed as targeted carriers to deliver
therapeutic molecules in the central nervous system (CNS). However, IONPs may damage …

Analyzing the mechanisms of iron oxide nanoparticles interactions with cells: A road from failure to success in clinical applications

A Frtús, B Smolková, M Uzhytchak, M Lunova… - Journal of Controlled …, 2020 - Elsevier
Iron oxide nanoparticles (IONPs) were the first generation of nanomaterials that reached real
clinic use. Particularly, several IONPs-based magnetic resonance imaging contrast agents …

Review on metal-based nanoparticles: role of reactive oxygen species in renal toxicity

P Makhdoumi, H Karimi, M Khazaei - Chemical Research in …, 2020 - ACS Publications
The rapidly emerging field of nanotechnology has offered innovative discoveries. Due to a
wide variety of nanotechnology applications in the industrial, medical, and consumptive …

Organ-specific toxicity of magnetic iron oxide-based nanoparticles

VV Chrishtop, VA Mironov, AY Prilepskii… - …, 2021 - Taylor & Francis
The unique properties of magnetic iron oxide nanoparticles determined their widespread
use in medical applications, the food industry, textile industry, which in turn led to …

Quercetin conjugated with superparamagnetic iron oxide nanoparticles improves learning and memory better than free quercetin via interacting with proteins involved …

E Amanzadeh, A Esmaeili, REN Abadi… - Scientific reports, 2019 - nature.com
Biomedical application of quercetin (QT) as an effective flavonoid has limitations due to its
low bioavailability. Superparamagnetic iron oxide nanoparticle (SPION) is a novel drug …

Effect of quercetin-conjugated superparamagnetic iron oxide nanoparticles on diabetes-induced learning and memory impairment in rats

S Ebrahimpour, A Esmaeili… - International Journal of …, 2018 - Taylor & Francis
Background Diabetes mellitus plays a causative role in cognitive decline. Newly,
neuroprotective effects of flavonoids have been widely investigated in neurodegenerative …

Synthesis of quercetin-metal complexes, in vitro and in silico anticholinesterase and antioxidant evaluation, and in vivo toxicological and anxiolitic activities

WMB da Silva, S de Oliveira Pinheiro, DR Alves… - Neurotoxicity …, 2020 - Springer
The level of acetylcholine, a neurotransmitter essential for processing memory and learning,
is lower in the brains of patients with Alzheimer's disease due to the higher concentration of …

Quercetin-conjugated superparamagnetic iron oxide nanoparticles (QCSPIONs) increases Nrf2 expression via miR-27a mediation to prevent memory dysfunction in …

S Ebrahimpour, SB Shahidi, M Abbasi, Z Tavakoli… - Scientific Reports, 2020 - nature.com
Oxidative stress is one of the earliest defects involved in the development of diabetes-
induced cognitive impairment. Nrf2 is the master regulator of the cellular antioxidant system …

Nanoencapsulation of basil essential oil alleviates the oxidative stress, genotoxicity and DNA damage in rats exposed to biosynthesized iron nanoparticles

AA El-Nekeety, ME Hassan, RR Hassan, OI Elshafey… - Heliyon, 2021 - cell.com
The application of essential oils in food and pharmaceutical sectors face several challenges
due to their sensitivity to oxidation process. Additionally, the biosynthesis of nanometals is …

Quercetin‑conjugated superparamagnetic iron oxide nanoparticles modulate glucose metabolism-related genes and miR-29 family in the hippocampus of diabetic rats

S Dini, M Zakeri, S Ebrahimpour, F Dehghanian… - Scientific Reports, 2021 - nature.com
Quercetin (QC) is a dietary bioflavonoid that can be conjugated with nanoparticles to
facilitate its brain bioavailability. We previously showed that quercetin-conjugated …