Neurobiology of BDNF in fear memory, sensitivity to stress, and stress-related disorders

M Notaras, M van den Buuse - Molecular psychiatry, 2020 - nature.com
Brain-derived neurotrophic factor (BDNF) is widely accepted for its involvement in resilience
and antidepressant drug action, is a common genetic locus of risk for mental illnesses, and …

Racial disparities in obesity treatment

AS Byrd, AT Toth, FC Stanford - Current obesity reports, 2018 - Springer
Abstract Purpose of Review Obesity rates in the USA have reached pandemic levels with
one third of the population with obesity in 2015–2016 (39.8% of adults and 18.5% of youth) …

Role of diet and exercise in aging, Alzheimer's disease, and other chronic diseases

S Khemka, A Reddy, RI Garcia, M Jacobs… - Ageing Research …, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease, characterized by
memory loss and multiple cognitive impairments. Genetic mutations cause a small …

Brain-derived neurotrophic factor (BDNF): novel insights into regulation and genetic variation

M Notaras, M van den Buuse - The Neuroscientist, 2019 - journals.sagepub.com
Since its discovery, brain-derived neurotrophic factor (BDNF) has spawned a literature that
now spans 35 years of research. While all neurotrophins share considerable overlap in …

The importance of a balanced ω-6 to ω-3 ratio in the prevention and management of obesity

AP Simopoulos, JJ DiNicolantonio - Open heart, 2016 - openheart.bmj.com
In 1980, a significant segment of the US population was already overweight or obese, but
obesity standards did not exist. Therefore, the National Institutes of Health (NIH) held the …

Metabolic homeostasis via BDNF and its receptors

B Podyma, K Parekh, AD Güler… - Trends in Endocrinology & …, 2021 - cell.com
Metabolic disorders result from dysregulation of central nervous system and peripheral
metabolic energy homeostatic pathways. To maintain normal energy balance, neural circuits …

Endocannabinoid modulation of homeostatic and non-homeostatic feeding circuits

BK Lau, D Cota, L Cristino, SL Borgland - Neuropharmacology, 2017 - Elsevier
The endocannabinoid system has emerged as a key player in the control of eating.
Endocannabinoids, including 2-arachidonoylglycerol (2-AG) and anandamide (AEA) …

Maternal obesity as a risk factor for brain development and mental health in the offspring

F Cirulli, C Musillo, A Berry - Neuroscience, 2020 - Elsevier
Maternal obesity plays a key role in the health trajectory of the offspring. Although research
on this topic has largely focused on the potential of this condition to increase the risk for child …

Intestinal dysbiosis, gut hyperpermeability and bacterial translocation: missing links between depression, obesity and type 2 diabetes

A Slyepchenko, M Maes… - Current …, 2016 - benthamdirect.com
The comorbid prevalence of major depressive disorder (MDD) with obesity and type II
diabetes mellitus reflects the existence of a subset of individuals with a complex common …

The pleiotropic potential of BDNF beyond neurons: implication for a healthy mind in a healthy body

MC Di Rosa, S Zimbone, MW Saab, MF Tomasello - Life, 2021 - mdpi.com
Brain-derived neurotrophic factor (BDNF) represents one of the most widely studied
neurotrophins because of the many mechanisms in which it is involved. Among these, a …