Aims The long-term impact of implantable device-related complications on the patient
outcome has not been thoroughly evaluated. The aims of this retrospective, bi-centre study …

BACKGROUND:: Flexible left ventricular (LV) pacing configurations are a useful component
of cardiac resynchronization therapy (CRT) systems for preventing high LV pacing …

Cardiac resynchronization therapy (CRT) requires permanent left ventricular (LV) pacing.
Coronary sinus (CS) lead placement is the first line clinical approach but can be difficult or …

Phrenic stimulation needs to be carefully managed at implantation and follow-up. Use of
bipolar/multipolar leads and of multiple pacing configurations is mandatory to increase the …

Aims Implantable cardioverter defibrillator (ICD) technology has become more complex,
particularly with respect to biventricular resynchronization devices. The incidence of …

BACKGROUND: Despite technical advancements, implantation of coronary sinus (CS) leads
may be challenging, and dislocation remains a relevant clinical problem. OBJECTIVE: The …

Aims Data on longer right to left ventricular activation delay (RV-LV AD) predicting clinical
outcome after cardiac resynchronization therapy (CRT) by left bundle branch block (LBBB) …

Cardiac resynchronization therapy (CRT) is a highly efficient treatment modality for patients
with severe congestive heart failure and intraventricular dyssynchrony. However, the high …

Aims The aim of our study was to investigate the long-term efficacy and safety of transseptal
endocardial left ventricular lead implantation (TELVLI). Methods and results Transseptal …

We report the biochemical and biophysical characterization of outer membrane protein X
(OmpX), an eight-stranded transmembrane β-barrel from E. coli, and compare the barrel …