Microbial production of advanced biofuels

J Keasling, H Garcia Martin, TS Lee… - Nature Reviews …, 2021 - nature.com
Concerns over climate change have necessitated a rethinking of our transportation
infrastructure. One possible alternative to carbon-polluting fossil fuels is biofuels produced …

Physiological limitations and opportunities in microbial metabolic engineering

J Montaño López, L Duran, JL Avalos - Nature Reviews Microbiology, 2022 - nature.com
Metabolic engineering can have a pivotal role in increasing the environmental sustainability
of the transportation and chemical manufacturing sectors. The field has already developed …

Engineering co-utilization of glucose and xylose for chemical overproduction from lignocellulose

J Gao, W Yu, Y Li, M Jin, L Yao, YJ Zhou - Nature Chemical Biology, 2023 - nature.com
Bio-refining lignocellulose could provide a sustainable supply of fuels and fine chemicals;
however, the challenges associated with the co-utilization of xylose and glucose typically …

Factors affecting the competitiveness of bacterial fermentation

JA Lee, HU Kim, JG Na, YS Ko, JS Cho, SY Lee - Trends in Biotechnology, 2023 - cell.com
Sustainable production of chemicals and materials from renewable non-food biomass using
biorefineries has become increasingly important in an effort toward the vision of 'net zero …

Peroxisomal metabolic coupling improves fatty alcohol production from sole methanol in yeast

X Zhai, J Gao, Y Li, M Grininger… - Proceedings of the …, 2023 - National Acad Sciences
Methanol is an ideal feedstock for chemical and biological manufacturing. Constructing an
efficient cell factory is essential for producing complex compounds through methanol …

Hyperproduction of 3-hydroxypropionate by Halomonas bluephagenesis

XR Jiang, X Yan, LP Yu, XY Liu, GQ Chen - Nature communications, 2021 - nature.com
Hydroxypropionic acid (3HP), an important three carbon (C3) chemical, is designated as
one of the top platform chemicals with an urgent need for improved industrial production …

Towards robust Pseudomonas cell factories to harbour novel biosynthetic pathways

NL Bitzenhofer, L Kruse, S Thies… - Essays in …, 2021 - portlandpress.com
Biotechnological production in bacteria enables access to numerous valuable chemical
compounds. Nowadays, advanced molecular genetic toolsets, enzyme engineering as well …

Engineering low-salt growth Halomonas Bluephagenesis for cost-effective bioproduction combined with adaptive evolution

L Zhang, Y Lin, X Yi, W Huang, Q Hu, Z Zhang… - Metabolic …, 2023 - Elsevier
Halophilic Halomonas bluephagenesis has been engineered to produce various added-
value bio-compounds with reduced costs. However, the salt-stress regulatory mechanism …

Screening non-conventional yeasts for acid tolerance and engineering Pichia occidentalis for production of muconic acid

ME Pyne, JA Bagley, L Narcross, K Kevvai… - Nature …, 2023 - nature.com
Saccharomyces cerevisiae is a workhorse of industrial biotechnology owing to the
organism's prominence in alcohol fermentation and the suite of sophisticated genetic tools …

[HTML][HTML] 合成生物学重要研究方向进展

丁明珠, 李炳志, 王颖, 谢泽雄, 刘夺, 元英进 - 合成生物学, 2020 - synbioj.cip.com.cn
摘要合成生物学作为一个新兴的交叉学科领域, 随着DNA 合成技术的进步和合成生物学理念的
深入, 多个研究方向取得了长足发展. 本文主要对基因回路, 基因组设计合成 …