5-Ene-4-thiazolidinones–An efficient tool in medicinal chemistry

D Kaminskyy, A Kryshchyshyn, R Lesyk - European journal of medicinal …, 2017 - Elsevier
The presented review is an attempt to summarize a huge volume of data on 5-ene-4-
thiazolidinones being a widely studied class of small molecules used in modern organic and …

Piperazine scaffold: A remarkable tool in generation of diverse pharmacological agents

M Shaquiquzzaman, G Verma, A Marella… - European journal of …, 2015 - Elsevier
Piperazine is one of the most sought heterocyclics for the development of new drug
candidates. This ring can be traced in a number of well established, commercially available …

Cytotoxic effect, enzyme inhibition, and in silico studies of some novel N-substituted sulfonyl amides incorporating 1,3,4-oxadiazol structural motif

Ö Güleç, C Türkeş, M Arslan, Y Demir, Y Yeni… - Molecular Diversity, 2022 - Springer
The acetylcholinesterase and carbonic anhydrase inhibitors (AChEIs and h CAIs) remain
key therapeutic agents for many bioactivities such as anti-Alzheimer and antiobesity …

Multi-target compounds acting in cancer progression: Focus on thiosemicarbazone, thiazole and thiazolidinone analogues

LRP de Siqueira, PAT de Moraes Gomes… - European Journal of …, 2019 - Elsevier
Currently, cancer and its progression to metastasis result in a large number of deaths. The
lack of new drugs, appropriate clinical trials for metastasis preventive drugs and incomplete …

A conceptual review of rhodanine: current applications of antiviral drugs, anticancer and antimicrobial activities

SM Mousavi, M Zarei, SA Hashemi… - Artificial cells …, 2019 - Taylor & Francis
Rhodanines are accepted as advantaged heterocycles in medicinal chemistry as one of the
4-thiazolidinones subtypes. The aim of this paper is to analyze the features of rhodanine and …

In vitro and in silico studies of fluorinated 2, 3‐disubstituted thiazolidinone‐pyrazoles as potential α‐amylase inhibitors and antioxidant agents

D Ganavi, R Ramu, V Kumar, SM Patil… - Archiv der …, 2022 - Wiley Online Library
As part of our effort to identify potent α‐amylase inhibitors, in the present study, a novel
series of fluorinated thiazolidinone‐pyrazole hybrid molecules were prepared by the …

Recent developments with rhodanine as a scaffold for drug discovery

D Kaminskyy, A Kryshchyshyn… - Expert Opinion on Drug …, 2017 - Taylor & Francis
Introduction: Rhodanines, as one of the 4-thiazolidinones subtypes, are recognized as
privileged heterocycles in medicinal chemistry. The main achievements include the …

New progress in azole compounds as antimicrobial agents

HZ Zhang, LL Gan, H Wang… - Mini reviews in medicinal …, 2017 - ingentaconnect.com
The increasing incidence of microbial resistance and newly emerging pathogens have
become a serious challenge for public health. More and more efforts have been directed to …

Antitubercular properties of thiazolidin-4-ones–A review

N Trotsko - European Journal of Medicinal Chemistry, 2021 - Elsevier
Thiazolidin-4-one scaffold has great potential for medicinal chemistry and is of interest to
scientists in view of wide spectrum of biological activity. This scaffold is often used for …

An efficient ultrasound-assisted CH3COONa catalyzed synthesis of thiazolidinone molecule: theoretical and nonlinear optical evaluations of thiazolidinone-Schiff base …

JK Salim, QMA Hassan, AM Jassem, HA Sultan… - Optical Materials, 2022 - Elsevier
Chemical synthesis, structural analysis, theoretical calculations and optical properties
exploration of (E)-2-((E)-(4-nitrobenzylidene) hydrazono)-3-phenyl-4-thiazolidinone 7 (C 16 …