Cell to cell communication is essential for the coordination and proper organization of
different cell types in multicellular systems. Cells exchange information through a multitude …

Angiogenesis is a multistep process and various molecules are involved in regulating it.
Extracellular vesicles are cell-derived particles, secreted from several types of cells and are …

Vasculogenesis and angiogenesis are critical processes in fetal circulation and placental
vasculature development. Placental mesenchymal stem cells (pMSC) are known to release …

Hypoxia plays an important role during the evolution of cancer cells and their
microenvironment. Emerging evidence suggests communication between cancer cells and …

Background Chronic myeloid leukemia (CML) is a clonal hematopoietic stem cell disorder in
which leukemic cells display a reciprocal t (9: 22) chromosomal translocation that results in …

Chronic myelogenous leukemia (CML) is a myeloproliferative disorder characterized by the
Bcr–Abl oncoprotein with constitutive tyrosine kinase activity. Exosomes are nanovesicles …

Introduction: Tumor-derived exosomes (TEX) and their role in tumor progression by
accelerating angiogenesis are of great current interest. A better understanding of the …

Background Recent findings indicate that exosomes released from cancer cells contain
microRNAs (miRNAs) that may be delivered to cells of tumor microenvironment. Results To …

Our understanding of the biology of the normal hematopoietic stem cell niche has increased
steadily due to improved murine models and sophisticated imaging tools. Less well …

Chronic myelogenous leukaemia (CML) is a clonal myeloproliferative disorder. Recent
evidence indicates that altered crosstalk between CML and mesenchymal stromal cells may …