The endocannabinoid system: a potential target for the treatment of various diseases
H Lowe, N Toyang, B Steele, J Bryant… - International journal of …, 2021 - mdpi.com
The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …
balance in internal environment (temperature, mood, and immune system) and energy input …
Cannabidiol for neurodegenerative disorders: A comprehensive review
Despite the significant advances in neurology, the cure for neurodegenerative conditions
remains a formidable task to date. Among various factors arising from the complex etiology …
remains a formidable task to date. Among various factors arising from the complex etiology …
Cannabinoid formulations and delivery systems: Current and future options to treat pain
B Stella, F Baratta, C Della Pepa, S Arpicco, D Gastaldi… - Drugs, 2021 - Springer
The field of Cannabis sativa L. research for medical purposes has been rapidly advancing in
recent decades and a growing body of evidence suggests that phytocannabinoids are …
recent decades and a growing body of evidence suggests that phytocannabinoids are …
[HTML][HTML] An overview of in vitro 3D models of the blood-brain barrier as a tool to predict the in vivo permeability of nanomedicines
A Pérez-López, AI Torres-Suárez… - Advanced Drug Delivery …, 2023 - Elsevier
The blood–brain barrier (BBB) prevents efficient drug delivery to the central nervous system.
As a result, brain diseases remain one of the greatest unmet medical needs. Understanding …
As a result, brain diseases remain one of the greatest unmet medical needs. Understanding …
[HTML][HTML] Lipid-core nanoparticles: Classification, preparation methods, routes of administration and recent advances in cancer treatment
P Graván, A Aguilera-Garrido, JA Marchal… - Advances in Colloid and …, 2023 - Elsevier
Nanotechnological drug delivery platforms represent a new paradigm for cancer
therapeutics as they improve the pharmacokinetic profile and distribution of …
therapeutics as they improve the pharmacokinetic profile and distribution of …
The endocannabinoid system: A target for cancer treatment
In recent years, the endocannabinoid system has received great interest as a potential
therapeutic target in numerous pathological conditions. Cannabinoids have shown an …
therapeutic target in numerous pathological conditions. Cannabinoids have shown an …
Cannabinoids, blood–brain barrier, and brain disposition
F Calapai, L Cardia, EE Sorbara, M Navarra… - Pharmaceutics, 2020 - mdpi.com
Potential therapeutic actions of the cannabinoids delta-9-tetrahydrocannabinol (THC) and
cannabidiol (CBD) are based on their activity as analgesics, anti-emetics, anti-inflammatory …
cannabidiol (CBD) are based on their activity as analgesics, anti-emetics, anti-inflammatory …
Cannabidiol and neurodegeneration: From molecular mechanisms to clinical benefits
Neurodegenerative disorders (NDs) such as Alzheimer's disease, Parkinson's disease,
Huntington's disease, multiple sclerosis, and amyotrophic lateral sclerosis are severe and …
Huntington's disease, multiple sclerosis, and amyotrophic lateral sclerosis are severe and …
Current challenges and opportunities for improved cannabidiol solubility
Cannabidiol (CBD), derived from the cannabis plant, has gained significant attention due to
its potential therapeutic benefits. However, one of the challenges associated with CBD …
its potential therapeutic benefits. However, one of the challenges associated with CBD …
[HTML][HTML] Biological effects of Cannabidiol on normal human healthy cell populations: Systematic review of the literature
S Pagano, M Coniglio, C Valenti, MI Federici… - Biomedicine & …, 2020 - Elsevier
A systematic review was performed to evaluate the biological effects of Cannabidiol (CBD),
one of the major components of Cannabis Sativa, on normal human healthy cell populations …
one of the major components of Cannabis Sativa, on normal human healthy cell populations …