The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

SK Hanks, AM Quinn, T Hunter - Science, 1988 - science.org
In recent years, members of the protein kinase family have been discovered at an
accelerated pace. Most were first described, not through the traditional biochemical …

[PDF][PDF] Animal cell cycles and their control

C Norbury, P Nurse - Annual review of biochemistry, 1992 - academia.edu
CELL CYCLE CONTROL IN ANIMALS 443 established in many cases. Nonetheless, the
phosphorylation of nuclear lamins to promote nuclear disassembly (25, 31, 38-40), and the …

Codon usage in yeast: cluster analysis clearly differentiates highly and lowly expressed genes

PM Sharp, TMF Tuohy, KR Mosurski - Nucleic acids research, 1986 - academic.oup.com
Codon usage data has been compiled for 110 yeast genes. Cluster analysis on relative
synonymous codon usage revealed two distinct groups of genes. One group corresponds to …

A Transmembrane Protein with a cdc2^+/CDC28-Related Kinase Activity Is Required for Signaling from the ER to the Nucleus

K Mori, W Ma, MJ Gething, J Sambrook - CELL-CAMBRIDGE MA-, 1993 - cell.com
In eukaryotic cells, the accumulation of unfolded proteins in the endoplasmic reticulum (ER)
triggers a signaling pathway from the ER to the nucleus. Several yeast mutants defective in …

Crystal structure of cyclin-dependent kinase 2

HL De Bondt, J Rosenblatt, J Jancarik, HD Jones… - Nature, 1993 - nature.com
Abstract Cyclin-dependent kinase 2 (CDK2) is a member of a highly conserved family of
protein klnases that regulate the eukaryotic cell cycle. The crystal structures of the human …

[HTML][HTML] Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

J Gyuris, E Golemis, H Chertkov, R Brent - Cell, 1993 - cell.com
We used the interaction trap, a yeast genetic selection for interacting proteins, to isolate
human cyclin-dependent kinase interactor 1 (Cdi1). In yeast, Cdi1 interacts with cyclin …

An overview of Cdk1-controlled targets and processes

JM Enserink, RD Kolodner - Cell division, 2010 - Springer
The cyclin dependent kinase Cdk1 controls the cell cycle, which is best understood in the
model organism S. cerevisiae. Research performed during the past decade has significantly …

Isolation of three novel human cyclins by rescue of G1 cyclin (Cln) function in yeast

DJ Lew, V Dulić, SI Reed - Cell, 1991 - cell.com
We have isolated a number of cDNAs derived from human mRNAs that are able to substitute
for Gl cyclin genes in S. cerevisiae. Several of these encode human cyclins A, Bl, and 82 …

Regulation of Cdc28 Cyclin-Dependent Protein Kinase Activity during the Cell Cycle of the Yeast Saccharomyces cerevisiae

MD Mendenhall, AE Hodge - Microbiology and Molecular Biology …, 1998 - Am Soc Microbiol
The cyclin-dependent protein kinase (CDK) encoded by CDC28 is the master regulator of
cell division in the budding yeast Saccharomyces cerevisiae. By mechanisms that, for the …

A yeast gene that is essential for release from glucose repression encodes a protein kinase

JL Celenza, M Carlson - Science, 1986 - science.org
The SNF1 gene plays a central role in carbon catabolite repression in the yeast
Saccharomyces cerevisiae, namely that SNF1 function is required for expression of glucose …