Venous thromboembolism: review of clinical challenges, biology, assessment, treatment, and modeling
C Watson, H Saaid, V Vedula, JC Cardenas… - Annals of Biomedical …, 2024 - Springer
Venous thromboembolism (VTE) is a massive clinical challenge, annually affecting millions
of patients globally. VTE is a particularly consequential pathology, as incidence is correlated …
of patients globally. VTE is a particularly consequential pathology, as incidence is correlated …
An improved particle method for simulating fluid-structure interactions: The multi-resolution SPH-VCPM approach
In this paper, the computational efficiency of our previous Smoothed Particle Hydrodynamics-
Volume Compensated Particle Method (SPH-VCPM) is enhanced by incorporating a multi …
Volume Compensated Particle Method (SPH-VCPM) is enhanced by incorporating a multi …
[HTML][HTML] Fluid-structure interaction of blood flow around a vein valve
Methods: In the present work, the blood flow through a venous valve considering the
flexibility of the vein wall and valve leaflets is investigated numerically. The governing …
flexibility of the vein wall and valve leaflets is investigated numerically. The governing …
A coupled smoothed particle hydrodynamics-volume compensated particle method (SPH-VCPM) for fluid structure interaction (FSI) modelling
A new unified particle model that couples the Smoothed Particle Hydrodynamics (SPH) and
a discontinuous approach known as the Volume Compensated Particle Method (VCPM) is …
a discontinuous approach known as the Volume Compensated Particle Method (VCPM) is …
Simulating the hydrodynamic conditions of the human ascending colon: a digital twin of the dynamic colon model
M Schütt, C O'farrell, K Stamatopoulos, CL Hoad… - Pharmaceutics, 2022 - mdpi.com
The performance of solid oral dosage forms targeting the colon is typically evaluated using
standardised pharmacopeial dissolution apparatuses. However, these fail to replicate …
standardised pharmacopeial dissolution apparatuses. However, these fail to replicate …
[HTML][HTML] A novel mono-physics particle-based approach for the simulation of cardiovascular fluid-structure interaction problems
Background and objective Fluid-structure interaction (FSI) is required in the study of several
cardiovascular engineering problems were the mutual interaction between the pulsatile …
cardiovascular engineering problems were the mutual interaction between the pulsatile …
[HTML][HTML] Fluid–structure interaction approach with smoothed particle hydrodynamics and particle–spring systems
This paper presents a novel three-dimensional fluid–structure interaction (FSI) approach,
where the meshless smoothed particle hydrodynamics (SPH) method is used to simulate the …
where the meshless smoothed particle hydrodynamics (SPH) method is used to simulate the …
[HTML][HTML] Development of a digital twin of a tablet that mimics a real solid dosage form: Differences in the dissolution profile in conventional mini-USP II and a …
M Schütt, K Stamatopoulos, HK Batchelor… - European Journal of …, 2022 - Elsevier
The performance of colon-targeted solid dosage forms is commonly assessed using
standardised pharmacopeial dissolution apparatuses like the USP II or the miniaturised …
standardised pharmacopeial dissolution apparatuses like the USP II or the miniaturised …
Modelling of thrombus formation using smoothed particle hydrodynamics method
In this paper a novel model, based on the smoothed particle hydrodynamics (SPH) method,
is proposed to simulate thrombus formation. This describes the main phases of the …
is proposed to simulate thrombus formation. This describes the main phases of the …
The role of valve stiffness in the insurgence of deep vein thrombosis
Z Schofield, HA Baksamawi, J Campos… - Communications …, 2020 - nature.com
Deep vein thrombosis is a life-threatening development of blood clots in deep veins.
Immobility and blood flow stagnancy are typical risk factors indicating that fluid dynamics …
Immobility and blood flow stagnancy are typical risk factors indicating that fluid dynamics …